Cycloartane Triterpenoids from Cassia occidentalis

	Cycloartane Triterpenoids from Cassia occidentalis
	Li SF 1,2; Di YT 1; Luo RH 3; Zheng YT 3; Wang YH 1; Fang X 1; Zhang Y1 ; Li L 4; He HP 1; Li SL1; Hao XJ1; lisl@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
	2012
发表期刊	PLANTA MEDICA
卷号	78 期号:8 页码:821-827
摘要	A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds were elucidated through detailed spectroscopic analyses, including 1D and 2D NMR techniques, and chemical methods. Compounds 2 and 5 showed modest anti-HIV-1 activities with EC50 values of 2.23 mu M and 4.36 mu M, respectively, in comparison to the positive control.; A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds were elucidated through detailed spectroscopic analyses, including 1D and 2D NMR techniques, and chemical methods. Compounds 2 and 5 showed modest anti-HIV-1 activities with EC50 values of 2.23 mu M and 4.36 mu M, respectively, in comparison to the positive control.
关键词	Cassia Occidentalis Leguminosae Cycloartane Triterpenoids Cycloccidentalic Acids a And b Cycloccidentalisides I-v
收录类别	SCI
语种	英语
WOS记录号	WOS:000304449300013
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7110
专题	科研部门_分子免疫药理学（郑永唐）科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	lisl@mail.kib.ac.cn; haoxj@mail.kib.ac.cn
作者单位	1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, P. R. China 2.Graduate University of Chinese Academy of Sciences, Beijing, P. R. China 3.Key Laboratory of Animal Models and Human Diseases Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, P. R. Chin 4.Yunnan Pharmacological Laboratories of Natural Products, Kunming Medical College, Kunming, Yunnan, P. R. China
推荐引用方式 GB/T 7714	Li SF,Di YT,Luo RH,et al. Cycloartane Triterpenoids from Cassia occidentalis[J]. PLANTA MEDICA,2012,78(8):821-827.
APA	Li SF.,Di YT.,Luo RH.,Zheng YT.,Wang YH.,...&haoxj@mail.kib.ac.cn.(2012).Cycloartane Triterpenoids from Cassia occidentalis.PLANTA MEDICA,78(8),821-827.
MLA	Li SF,et al."Cycloartane Triterpenoids from Cassia occidentalis".PLANTA MEDICA 78.8(2012):821-827.

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