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	Relationships of mRNA-protein secondary structures in the human beta-globin gene HBB and four variants
	Li YF1; Ye DH1; Zhang W2; Wang CM1; Liu CQ*1,3; Cao H*1; liucq@ynu.edu.cn; caohuai@ynu.edu.cn
	2012
发表期刊	CHINESE SCIENCE BULLETIN
卷号	57期号:30页码:3898-3907
合作性质	其它
摘要	Single nucleotide polymorphism is an interesting problem that can alter gene expression, recode amino acids and affect protein function. Protein structural changes have generally been attributed to amino acid replacements, and only a few research efforts have examined the effects of mRNA structural changes to the conformation of the corresponding protein coded by the mRNA. In the present study, the human beta-globin HBB gene and four variants were examined. The mRNA secondary structures were constructed using the dynamic extended folding method and the encoded protein secondary structures were obtained from related databases. Comparisons were performed between these structures before and after mutations were introduced into the mature mRNAs and the proteins. We focused on the structural changes from mRNA to protein and found that regular protein conformations tend to match stable mRNA regions, whereas irregular protein conformations, such as beta/gamma turns and random coils, often match unstable mRNA regions. Mutations within unstable regions can alter the mRNA secondary structure and leave footprints in the protein structure. Comparison of the mRNA-protein secondary structure relationships represents a potential strategy to explore protein functional changes.
关键词	Hbb Gene Mutation Mrna Protein Secondary Structure Relationships
资助者	This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018).
收录类别	SCI
语种	英语
资助者	This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018). ; This work was supported by the National Natural Science Foundation of China (30971454 and 90208018).
WOS记录号	WOS:000309350000013
引用统计
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7128
专题	其他
通讯作者	liucq@ynu.edu.cn; caohuai@ynu.edu.cn
作者单位	1.Modern Biological Research Center, Yunnan University, Kunming 650091, China 2.Department of Cell Biology and Genetics, Kunming Medical University, Kunming 650031, China 3.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
推荐引用方式 GB/T 7714	Li YF,Ye DH,Zhang W,et al. Relationships of mRNA-protein secondary structures in the human beta-globin gene HBB and four variants[J]. CHINESE SCIENCE BULLETIN,2012,57(30):3898-3907.
APA	Li YF.,Ye DH.,Zhang W.,Wang CM.,Liu CQ*.,...&caohuai@ynu.edu.cn.(2012).Relationships of mRNA-protein secondary structures in the human beta-globin gene HBB and four variants.CHINESE SCIENCE BULLETIN,57(30),3898-3907.
MLA	Li YF,et al."Relationships of mRNA-protein secondary structures in the human beta-globin gene HBB and four variants".CHINESE SCIENCE BULLETIN 57.30(2012):3898-3907.

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2012110601.pdf（1179KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

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