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	Molecular dynamics simulation of PNPLA3 I148M polymorphism reveals reduced substrate access to the catalytic cavity
	Xin YN1,2; Zhao YQ3; Lin ZH2; Jiang XJ2; Xuan SY*1,2; Huang JF*3,4; dxyxyn@163.com; huangjf@mail.kiz.ac.cn
	2013
发表期刊	PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
卷号	81期号:3页码:406-414
合作性质	其它
摘要	A missense mutation I148M in PNPLA3 (patatin-like phospholipase domain-containing 3 protein) is significantly correlated with nonalcoholic fatty liver disease (NAFLD). To glean insights into mutation's effect on enzymatic activity, we performed molecular dynamics simulation and flexible docking studies. Our data show that the size of the substrate-access entry site is significantly reduced in mutants, which limits the access of palmitic acid to the catalytic dyad. Besides, the binding free energy calculations suggest low affinity for substrate to mutant enzyme. The substrate-bound system simulations reveal that the spatial arrangement of palmitic acid is distinct in wild-type from that in mutant. The substrate recognition specificity is lost due to the loop where the I148M mutation was located. Our results provide strong evidence for the mechanism by which I148M affects the enzyme activity and suggest that mediating the dynamics may offer a potential avenue for NAFLD.
关键词	Pnpla3 Nonalcoholic Fatty Liver Disease Missense Mutation Molecular Dynamics Simulations
资助者	National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300.
收录类别	SCI
语种	英语
资助者	National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300. ; National Natural Science Foundation of China; Grant numbers: 31123005, 81170337; Grant sponsor: Chinese Academy of Sciences; Grant number: Y002731071; Grant sponsor: Shandong Provincial Natural Science Foundation, China; Grant number: ZR2009CM015; Grant sponsor: National Basic Research Program of China; Grant number: 2009CB941300.
WOS记录号	WOS:000314179600005
引用统计	被引频次：11[WOS]   [WOS记录]     [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7220
专题	结构生物信息学 遗传资源与进化国家重点实验室
通讯作者	dxyxyn@163.com; huangjf@mail.kiz.ac.cn
作者单位	1.College of Medicine and Pharmaceutics, Ocean University of China, Qingdao 266003, Shandong Province, China 2.Qingdao Municipal Hospital, Qingdao 266021, Shandong Province, China 3.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China 4.Kunming Institute of Zoology-Chinese University of Hongkong Joint Research Center for Bio-resources and Human Disease Mechanisms, Kunming 650223, China
推荐引用方式 GB/T 7714	Xin YN,Zhao YQ,Lin ZH,et al. Molecular dynamics simulation of PNPLA3 I148M polymorphism reveals reduced substrate access to the catalytic cavity[J]. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS,2013,81(3):406-414.
APA	Xin YN.,Zhao YQ.,Lin ZH.,Jiang XJ.,Xuan SY*.,...&huangjf@mail.kiz.ac.cn.(2013).Molecular dynamics simulation of PNPLA3 I148M polymorphism reveals reduced substrate access to the catalytic cavity.PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS,81(3),406-414.
MLA	Xin YN,et al."Molecular dynamics simulation of PNPLA3 I148M polymorphism reveals reduced substrate access to the catalytic cavity".PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 81.3(2013):406-414.

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2013030201.pdf（1086KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

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