KIZ OpenIR  > 科研部门  > 生物毒素与人类疾病(张云)
Activation of protease-activated receptor (PAR) 1 by frog trefoil factor (TFF) 2 and PAR4 by human TFF2.
Zhang Y1,2,3; Yu GY1,2,3; Wang YJ1,2,3; Xiang Y1,2,3; Gao Q1,2,3; Jiang P1,2,3; Zhang JT1,2,3; Lee WH1,2; Zhang Y*1,2; zhangy@mail.kiz.ac.cn
2011
发表期刊CELLULAR AND MOLECULAR LIFE SCIENCES
卷号68期号:22页码:3771-3780
合作性质其它
摘要Trefoil factors (TFFs) promote epithelial cell migration to reseal superficial wounds after mucosal injury, but their receptors and the molecular mechanisms underlying this process are poorly understood. In this study, we showed that frog TFF2 activates protease-activated receptor (PAR) 1 to induce human platelet aggregation. Based on this result, we further tested the involvement of PARs in human TFF2 (hTFF2)-promoted mucosal healing. hTFF2-stimulated migration of epithelial HT-29 cells was largely inhibited by PAR4 depletion with small interfering RNAs but not by PAR1 or PAR2 depletion. The PAR4-negative epithelial cell lines AGS and LoVo were highly responsive to hTFF2 as assessed by phosphorylation of ERK1/2 and cell migration upon PAR4 expression. Our findings suggest that hTFF2 promotes cell migration via PAR4. These findings will be helpful in further investigations into the functions and molecular mechanisms of TFFs and PARs in physiology and disease.
关键词Trefoil Factor Protease-activated Receptor Epithelial Cells Cell Migration Mucosal Healing Platelet Activation
资助者This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088).
收录类别SCI
语种英语
资助者This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088). ; This work was supported by grants from the National Basic Research Program of China (973 Program, 2010CB529800), the Chinese National Natural Science Foundation (30630014, 30570359, and 30870304), and the Chinese Academy of Sciences ‘‘Key Research Direction’’ (KSCX2-YW-R-088).
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/7329
专题科研部门_生物毒素与人类疾病(张云)
科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者zhangy@mail.kiz.ac.cn
作者单位1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China
2.Kunming Institute of Zoology, The Chinese Academy of Sciences, 32 East Jiaochang Road, Kunming, Yunnan 650223, China
3.Graduate School of the Chinese Academy of Sciences, Beijing 100049, China
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Zhang Y,Yu GY,Wang YJ,et al. Activation of protease-activated receptor (PAR) 1 by frog trefoil factor (TFF) 2 and PAR4 by human TFF2.[J]. CELLULAR AND MOLECULAR LIFE SCIENCES,2011,68(22):3771-3780.
APA Zhang Y.,Yu GY.,Wang YJ.,Xiang Y.,Gao Q.,...&zhangy@mail.kiz.ac.cn.(2011).Activation of protease-activated receptor (PAR) 1 by frog trefoil factor (TFF) 2 and PAR4 by human TFF2..CELLULAR AND MOLECULAR LIFE SCIENCES,68(22),3771-3780.
MLA Zhang Y,et al."Activation of protease-activated receptor (PAR) 1 by frog trefoil factor (TFF) 2 and PAR4 by human TFF2.".CELLULAR AND MOLECULAR LIFE SCIENCES 68.22(2011):3771-3780.
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