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	BRG1 Is Required for Formation of Senescence-Associated Heterochromatin Foci Induced by Oncogenic RAS or BRCA1 Loss
	Tu ZG1; Zhuang XY2; Yao YG2; Zhang RG*1; rzhang@wistar.org
	2013
发表期刊	MOLECULAR AND CELLULAR BIOLOGY
卷号	33期号:9页码:1819-1829
合作性质	其它
摘要	Cellular senescence is an important tumor suppression mechanism. We have previously reported that both oncogene-induced dissociation of BRCA1 from chromatin and BRCA1 knockdown itself drive senescence by promoting formation of senescence-associated heterochromatin foci (SAHF). However, the molecular mechanism by which BRCA1 regulates SAHF formation and senescence is unclear. BRG1 is a chromatin-remodeling factor that interacts with BRCA1 and pRB. Here we show that BRG1 is required for SAHF formation and senescence induced by oncogenic RAS or BRCA1 loss. The interaction between BRG1 and BRCA1 is disrupted during senescence. This correlates with an increased level of chromatin-associated BRG1 in senescent cells. BRG1 knockdown suppresses the formation of SAHF and senescence, while it has no effect on BRCA1 chromatin dissociation induced by oncogenic RAS, indicating that BRG1 functions downstream of BRCA1 chromatin dissociation. Furthermore, BRG1 knockdown inhibits SAHF formation and senescence induced by BRCA1 knockdown. Conversely, BRG1 overexpression drives SAHF formation and senescence in a DNA damage-independent manner. This effect depends upon BRG1's chromatin-remodeling activity as well as the interaction between BRG1 and pRB. Indeed, the interaction between BRG1 and pRB is enhanced during senescence. Chromatin immunoprecipitation analysis revealed that BRG1's association with the human CDKN2A and CDKN1A gene promoters was enhanced during senescence induced by oncogenic RAS or BRCA1 knockdown. Consistently, knockdown of pRB, p21(CIP1), and p16(INK4a), but not p53, suppressed SAHF formation induced by BRG1. Together, these studies reveal the molecular underpinning by which BRG1 acts downstream of BRCA1 to promote SAHF formation and senescence.
资助者	This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute.
收录类别	SCI
语种	英语
资助者	This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute. ; This work was supported by a NIH/NCI grant (R01CA160331toR.Z.) and, in part, by a DOD award (OC093420 to R.Z.). Support of core facil- ities used in this study was provided by Cancer Center Support Grant CA010815 to The Wistar Institute.
WOS记录号	WOS:000317273300012
引用统计	被引频次：28[WOS]   [WOS记录]     [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7419
专题	科研部门_疾病机理遗传学和进化医学学科组（姚永刚） 科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	rzhang@wistar.org
作者单位	1.Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania, USA 2.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Kunming, Yunnan, China
推荐引用方式 GB/T 7714	Tu ZG,Zhuang XY,Yao YG,et al. BRG1 Is Required for Formation of Senescence-Associated Heterochromatin Foci Induced by Oncogenic RAS or BRCA1 Loss[J]. MOLECULAR AND CELLULAR BIOLOGY,2013,33(9):1819-1829.
APA	Tu ZG,Zhuang XY,Yao YG,Zhang RG*,&rzhang@wistar.org.(2013).BRG1 Is Required for Formation of Senescence-Associated Heterochromatin Foci Induced by Oncogenic RAS or BRCA1 Loss.MOLECULAR AND CELLULAR BIOLOGY,33(9),1819-1829.
MLA	Tu ZG,et al."BRG1 Is Required for Formation of Senescence-Associated Heterochromatin Foci Induced by Oncogenic RAS or BRCA1 Loss".MOLECULAR AND CELLULAR BIOLOGY 33.9(2013):1819-1829.

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2013050902.pdf（2629KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

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