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	Effects of Amino Acid Deletion and Substitution on the Chemical Properties, Biological Activities of the Frog Peptide Palustrin-OG1
	Xie YG1; Liu YF1; Luan C1; Han FF1; Lai R2; Groleau D3; Feng J1; Wang YZ*1; yzwang@zju.edu.cn
	2013
发表期刊	PROTEIN AND PEPTIDE LETTERS
卷号	20期号:7页码:813-819
合作性质	其它
摘要	Palustrin-OG1 (OG1) is a host defense peptide isolated from the frog Odorrana grahami. In this study, we analyzed the chemical properties, antimicrobial activities and cytotoxicities of OG1 and its derivatives to identify the most promising peptide as an antimicrobial agent. By increasing the net positive charge, amphipathicity and decreasing the mean hydrophobicity of OG1, the derivative named as OG2 exerted higher antimicrobial activity against bacteria but lower cytotoxicity against both porcine erythrocytes and peripheral blood mononuclear cells than did OG1 (P<0.01). After substitution of Cys residues of OG2 by Ala or Trp residues, two derivatives named as OG2A and OG2W were less effective against bacteria and induced greater hemolysis than did OG2, indicating the importance of Cys residues. The substitution of the C-terminal Thr of OG2 resulted OG2N, which decreased the cytotoxicity and improved killing kinetics against gram-positive bacteria by the rapid damage of cell wall and
关键词	Palustrin-og1 Host Defense Peptide Antimicrobial Activity Killing Kinetics Cytotoxicity
资助者	This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6).
收录类别	SCI
语种	英语
资助者	This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6). ; This study was supported by The National High Tech- nology Research and Development Program of China (863 Program, No. 2007AA100602), National 12th 5-year Plan (No. NC2010CA0026) and Foundation for the Author of National Excellent Doctoral Dissertation of China (FANEDD, Grant No. 2007B6).
WOS记录号	WOS:000319499400012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7558
专题	科研部门_天然药物功能蛋白质学科组（赖仞）
通讯作者	yzwang@zju.edu.cn
作者单位	1.Key laboratory of Animal Nutrition and Feed Science of Ministry of Agriculture, Key Laboratory of Feed and Animal Nutrition of Zhejiang Province, Institute of Feed Science, Zhejiang University, Hangzhou, Zhejiang, PR China 2.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, PR China 3.Biotechnology Research Insti- tute, National Research Council, Montreal, Quebec, Canada
推荐引用方式 GB/T 7714	Xie YG,Liu YF,Luan C,et al. Effects of Amino Acid Deletion and Substitution on the Chemical Properties, Biological Activities of the Frog Peptide Palustrin-OG1[J]. PROTEIN AND PEPTIDE LETTERS,2013,20(7):813-819.
APA	Xie YG.,Liu YF.,Luan C.,Han FF.,Lai R.,...&yzwang@zju.edu.cn.(2013).Effects of Amino Acid Deletion and Substitution on the Chemical Properties, Biological Activities of the Frog Peptide Palustrin-OG1.PROTEIN AND PEPTIDE LETTERS,20(7),813-819.
MLA	Xie YG,et al."Effects of Amino Acid Deletion and Substitution on the Chemical Properties, Biological Activities of the Frog Peptide Palustrin-OG1".PROTEIN AND PEPTIDE LETTERS 20.7(2013):813-819.

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bj01284786.pdf（279KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

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