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	Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors
	He QQ1; Zhang X2,3; Yang LM2; Zheng YT2; Chen F*1; rfchen@fudan.edu.cn
	2013
发表期刊	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
卷号	28期号:4页码:671-676
合作性质	其它
摘要	A series of new quinolone-3-carboxylic acids as HIV-1 integrase inhibitors featuring a fluorine atom at C-5 position were synthesized and evaluated for their antiviral activity in C8166 cell culture. These newly synthesized compounds showed anti-HIV activity against wild-type virus with an EC50 value ranging from 29.85 to 0.032 mu M. The most active compound 4e exhibited activity against wild-type virus and the mutant virus A17 with an EC50 value of 0.032 and 0.082 mu M, respectively. Preliminary structure-activity relationship of these 5-fluoroquinolone-3-carboxylic acids was also investigated.
关键词	Hiv-1 Integrase Inhibitor 5-fluoroquinolone-3-carboxylic Acids Anti-hiv Activity Metal Chelating Structure-activity Relationship
资助者	The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006).
收录类别	SCI
语种	英语
资助者	The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006). ; The work was also supported in part by grants from the National Natural Science Foundation of China (20872018), from Chinese Academy of Sciences (KSCX2-YW-R-185), from the Eleventh Five- Year Key Scientific and Technological Program of China (2009ZX09501-029), and from National Basic Research Program of China (2009CB5223006).
WOS记录号	WOS:000321693400003
引用统计	被引频次：7[WOS]   [WOS记录]     [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7592
专题	科研部门_分子免疫药理学（郑永唐） 科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	rfchen@fudan.edu.cn
作者单位	1.Department of Chemistry, Fudan University, Shanghai, P R China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P R China 3.Faculty of Pharmacy, Kunming Medical University, Kunming, P R China
推荐引用方式 GB/T 7714	He QQ,Zhang X,Yang LM,et al. Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors[J]. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY,2013,28(4):671-676.
APA	He QQ,Zhang X,Yang LM,Zheng YT,Chen F*,&rfchen@fudan.edu.cn.(2013).Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors.JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY,28(4),671-676.
MLA	He QQ,et al."Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors".JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 28.4(2013):671-676.

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