| Association of genetic variationin CACNA1C with bipolar disorder in Han Chinese | |
| Zhang X1; Zhang C*2,3; Wu ZG2; Wang ZW2,4; Peng DH2; Chen J2; Hong W2; Yuan CM2; Li ZZ5; Yu SY6; Fang YR*2; zhangchen645@gmail.com, zhangchen1977@yahoo.com.cn; yirufang@yahoo.com.cn | |
| 2013 | |
| 发表期刊 | JOURNAL OF AFFECTIVE DISORDERS
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| 卷号 | 150期号:2页码:261-265 |
| 摘要 | Background: A growing body of evidence highlights the existence of shared genetic susceptibility to both major depressive disorder (MDD) and bipolar disorder (BD), suggesting some potential genetic overlap between the disorders. Genome-wide association studies have identified consistent association of single nucleotide polymorphisms of the alpha-1 C subunit of the L-Lype voltage gated calcium channel gene (CACNA1C) with MDD and BD, suggesting CACNA1C as a promising candidate gene for susceptibility to mood disorders. In the present study, we tested the association of CACNA1C with MDD and BD in Han Chinese. Methods: We genotyped three potentially functional polymorphisms in 635 MDD patients, 286 BD patients and 730 normal, control patients. Results: The genotype frequencies of SNP rs1051375 showed statistically significant differences between the BD and control groups (P=0.005). At the allele level, the difference of G allele frequency of rs 105137 5 between BD patients and control subjects was also significant (P=0.011; OR=1.30, 95% CI: 1.06-1.58). We found that GG genotype of rs1051375 carriers had a lower age at onset than those with the AG or AA genotype, and the mean +/- standard deviation ages at onset of GG, AG and AA carriers were 24.04 +/- 4.22, 25.76 +/- 4.75 and 25.78 +/- 4.33 years, respectively. Neither genotype nor allele frequencies of the three polymorphisms were found to be significantly different between the MOD patients and control subjects. Limitations: The relative small sample size in BD group should be considered a limitation of this study. Conclusions: Our initial findings support a potential association of CACNA1C as a genetic risk factor for BD susceptibility |
| 关键词 | Major Depressive Disorder Bipolar Disorder Cacna1c Polymorphism Age Atonset |
| 资助者 | This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). |
| 语种 | 英语 |
| 资助者 | This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). ; This work was supported by the National Natural Science Foundation of China Nos. (30971047 and 81000581), Shanghai Science & Technology Development Foundation (12140904200) and the National Key Clinical Disciplines at Shanghai Mental Health Center (OMA-MH2011-873). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/7657 |
| 专题 | 分子病理学 科研部门_动物模型与人类重大疾病机理重点实验室 |
| 通讯作者 | zhangchen645@gmail.com, zhangchen1977@yahoo.com.cn; yirufang@yahoo.com.cn |
| 作者单位 | 1.Department of Psychiatry, Tongji Hospital, Tongji University School of Medicine, Shanghai, China 2.Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China 3.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China 4.Department of Psychiatry, Hongkou District Mental Health Center of Shanghai, Shanghai, China 5.Department of Neurology, Shanghai Changhai Hospital, Secondary Military Medical University, Shanghai, China 6.Department of Genetics, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China |
| 推荐引用方式 GB/T 7714 | Zhang X,Zhang C*,Wu ZG,et al. Association of genetic variationin CACNA1C with bipolar disorder in Han Chinese[J]. JOURNAL OF AFFECTIVE DISORDERS,2013,150(2):261-265. |
| APA | Zhang X.,Zhang C*.,Wu ZG.,Wang ZW.,Peng DH.,...&yirufang@yahoo.com.cn.(2013).Association of genetic variationin CACNA1C with bipolar disorder in Han Chinese.JOURNAL OF AFFECTIVE DISORDERS,150(2),261-265. |
| MLA | Zhang X,et al."Association of genetic variationin CACNA1C with bipolar disorder in Han Chinese".JOURNAL OF AFFECTIVE DISORDERS 150.2(2013):261-265. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 2013092101.pdf（394KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
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