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	Molecular dynamics simulations and statistical coupling analysis reveal functional coevolution network of oncogenic mutations in the CDKN2A-CDK6 complex
	Wang JW2; Zhao YQ1; Wang YJ3; Huang JF*1,4; huangjf@mail.kiz.ac.cn
	2013
发表期刊	FEBS LETTERS
卷号	587期号:2页码:136-141
合作性质	其它
摘要	Coevolution between proteins is crucial for understanding protein-protein interaction. Simultaneous changes allow a protein complex to maintain its overall structural-functional integrity. In this study, we combined statistical coupling analysis (SCA) and molecular dynamics simulations on the CDK6-CDKN2A protein complex to evaluate coevolution between proteins. We reconstructed an inter-protein residue coevolution network, consisting of 37 residues and 37 interactions. It shows that most of the coevolved residue pairs are spatially proximal. When the mutations happened, the stable local structures were broken up and thus the protein interaction was decreased or inhibited, with a following increased risk of melanoma. The identification of inter-protein coevolved residues in the CDK6-CDKN2A complex can be helpful for designing protein engineering experiments
关键词	Inter-protein Coevolution Oncogenic Mutations Melanoma Molecular Dynamics Simulation Cdk6-cdkn2a Complex
资助者	This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300).
收录类别	SCI
语种	英语
资助者	This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300). ; This work was supported by the National Natural Science Foun- dation of China (Grant No. 31123005), Chinese Academy of Sci- ences (Grant No. Y002731071), and the National Basic Research Program of China (Grant No. 2009CB941300).
WOS记录号	WOS:000313635400005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7664
专题	结构生物信息学 科研部门_动物模型与人类重大疾病机理重点实验室 遗传资源与进化国家重点实验室
通讯作者	huangjf@mail.kiz.ac.cn
作者单位	1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 32 Eastern Jiaochang Road, Kunming, Yunnan 650223, China 2.Yantai Yuhuangding Hospital, Yantai, Shandong Province 264000, China 3.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China 4.Kunming Institute of Zoology, Chinese University of Hongkong, Joint Research Center for Bio-resources and Human Disease Mechanisms, Kunming 650223, China
推荐引用方式 GB/T 7714	Wang JW,Zhao YQ,Wang YJ,et al. Molecular dynamics simulations and statistical coupling analysis reveal functional coevolution network of oncogenic mutations in the CDKN2A-CDK6 complex[J]. FEBS LETTERS,2013,587(2):136-141.
APA	Wang JW,Zhao YQ,Wang YJ,Huang JF*,&huangjf@mail.kiz.ac.cn.(2013).Molecular dynamics simulations and statistical coupling analysis reveal functional coevolution network of oncogenic mutations in the CDKN2A-CDK6 complex.FEBS LETTERS,587(2),136-141.
MLA	Wang JW,et al."Molecular dynamics simulations and statistical coupling analysis reveal functional coevolution network of oncogenic mutations in the CDKN2A-CDK6 complex".FEBS LETTERS 587.2(2013):136-141.

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2013092404.pdf（1218KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

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