Since the publication of the first animal genome sequence in the year of 1998, hundreds of animals have their whole genome sequences and numerous animals have their own re-sequenced populations, accompanied by the rapid development and explosive applications of DNA sequencing technologies in recent years. Based on the technological advances and subsequent accumulation of large quantity of genomic data, evolutionary genomics has become one of the most rapidly advancing disciplines in biology. I investigated animal evolutionary genomics study under different scales. By reviewing and analyzing animal evolutionary genomics of phylogenetically distant species, close species or within specie, I presented a comprehensive landscape of large scale and inter-species animal evolutionary genomics. Meanwhile, the single-cell sequencing study on a myeloproliferative neoplasm cell population indicated a micro-scale evolutionary pattern within an individual. Finally, we performed characteristic comparison of evolutionary genomics studies under different scales. This dissertation shed new light on understanding of animal biodiversity and evolution from different angles.
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