The sheep genome illuminates biology of the rumen and lipid metabolism

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	The sheep genome illuminates biology of the rumen and lipid metabolism
	Jiang Y 1,2,3; Xie M 4; Chen WB 4; Talbot R 5; Maddox JF 6; Faraut T 7; Wu CH 6; Muzny DM 8; Li YX 4; Zhang WG 1,9,10; Wang W 1; brian.dalrymple@csiro.au
	2014
发表期刊	SCIENCE
卷号	344 期号:6188 页码:1168-1173
摘要	Sheep (Ovis aries) are a major source of meat, milk, and fiber in the form of wool and represent a distinct class of animals that have a specialized digestive organ, the rumen, that carries out the initial digestion of plant material. We have developed and analyzed a high-quality reference sheep genome and transcriptomes from 40 different tissues. We identified highly expressed genes encoding keratin cross-linking proteins associated with rumen evolution. We also identified genes involved in lipid metabolism that had been amplified and/or had altered tissue expression patterns. This may be in response to changes in the barrier lipids of the skin, an interaction between lipid metabolism and wool synthesis, and an increased role of volatile fatty acids in ruminants compared with nonruminant animals.
收录类别	SCI
语种	英语
WOS记录号	WOS:000336791200050
引用统计	被引频次：203[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7910
专题	基因起源组遗传资源与进化国家重点实验室
通讯作者	brian.dalrymple@csiro.au
作者单位	1.Chinese Acad Sci, Kunming Inst Zool, State Key Lab Genet Resources & Evolut, Kunming 650223, Peoples R China 2.Commonwealth Sci & Ind Res Org Anim Food & Hlth S, St Lucia, Qld 4067, Australia 3.Northwest A&F Univ, Coll Anim Sci & Technol, Yangling 712100, Peoples R China 4.BGI Shenzhen, Shenzhen 518083, Peoples R China 5.Univ Edinburgh, Ediburgh Genom, Easter Bush EH25 9RG, Midlothian, Scotland 6.Utah State Univ, Logan, UT 84322 USA 7.INRA, Lab Genet Cellulaire, UMR 444, F-31326 Castanet Tolosan, France 8.Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA 9.Inner Mongolia Agr Univ, Hohhot 010018, Peoples R China 10.Nei Mongol Bioinformat, Inst ATCG, Hohhot, Peoples R China 11.Univ Otago, Dept Anat, Dunedin 9054, New Zealand 12.AgResearch, Invermay Agr Ctr, Mosgiel 9053, New Zealand 13.Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England 14.Univ Copenhagen, Dept Biol, DK-2100 Copenhagen O, Denmark 15.Washington State Univ, USDA ARS, Anim Dis Res Unit, Pullman, WA 99164 USA 16.Washington State Univ, Dept Vet Microbiol & Pathol, Pullman, WA 99164 USA 17.Sichuan Agr Univ, Maize Res Inst, Chengdu 611130, Peoples R China 18.Lanzhou Inst Husb & Pharmaceut Sci, Lanzhou 730050, Peoples R China 19.Univ Copenhagen, Dept Biol, DK-2200 Copenhagen N, Denmark 20.European Bioinformat Inst, European Mol Biol Lab, Cambridge CB10 1SA, England
推荐引用方式 GB/T 7714	Jiang Y,Xie M,Chen WB,et al. The sheep genome illuminates biology of the rumen and lipid metabolism[J]. SCIENCE,2014,344(6188):1168-1173.
APA	Jiang Y.,Xie M.,Chen WB.,Talbot R.,Maddox JF.,...&brian.dalrymple@csiro.au.(2014).The sheep genome illuminates biology of the rumen and lipid metabolism.SCIENCE,344(6188),1168-1173.
MLA	Jiang Y,et al."The sheep genome illuminates biology of the rumen and lipid metabolism".SCIENCE 344.6188(2014):1168-1173.

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2014062001.pdf（1292KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文