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	Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression
	Hong W1; Fan JB3; Yuan CM1; Zhang C1,2; Hu YY1; Peng DH1; Wang Y1; Huang J1; Li ZZ1; Yu SY1; Liu XH1; Wu ZG1; Chen J1; Yi ZH1; Xu L2; Fang YR*1; yirufang@gmail.com
	2014
发表期刊	NEUROREPORT
卷号	25期号:10页码:753-755
合作性质	其它
摘要	The aim of the current study was to investigate whether the levels of mRNA expression of brain-derived neurotrophin factor (BDNF) and a related gene MEK1 were more obviously decreased in treatment-resistant depression (TRD). In total, 50 patients with major depressive disorder (including 26 with TRD and 24 with treatment-responsive depression) and 48 healthy controls were enrolled. BDNF and MEK1 mRNA levels in blood samples from all patients and controls were measured using reverse transcriptase-PCR. BDNF and MEK1 mRNA levels were significantly reduced in patients with major depressive disorder when compared with healthy controls (BDNF: P<0.01; MEK1: P<0.001), as well as among treatment-resistant depressive patients as compared with treatment-responsive depressive patients (BDNF: P<0.001; MEK1: P<0.01). Our findings support the hypothesis that BDNF and MEK1 mRNA expression levels are more obviously decreased in patients with TRD.
关键词	Brain-derived Neurotrophin Factor Mitogen-activated Protein Kinase Kinase 1 Treatment-resistant Depression Treatment-responsive Depression
资助者	This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990.
收录类别	SCI
语种	英语
资助者	This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990. ; This study was supported by the ‘12th five-year plan’ of National Key Technologies R&D Program (2012BAI01B04), National Natural Science Foundation of China (91232719), National Key Clinical Disciplines at Shanghai Mental Health Center (2011-873), National High-tech R&D Program (863 Program; 2006AA02Z430), the Program of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine (2011-YJ-06), and Program of Health Department of Shanghai Muni- cipal Government(2013-71). Dr Jinbo Fan was supported in part by NIH/NCRR CTSA KL2RR024990.
WOS记录号	WOS:000337728800005
引用统计	被引频次：18[WOS]   [WOS记录]     [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7914
专题	科研部门_学习记忆的分子神经机制（徐林） 科研部门_动物模型与人类重大疾病机理重点实验室 分子病理学
通讯作者	yirufang@gmail.com
作者单位	1.Shanghai Mental Health Center, Division of Mood Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai 2.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, China 3.Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
推荐引用方式 GB/T 7714	Hong W,Fan JB,Yuan CM,et al. Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression[J]. NEUROREPORT,2014,25(10):753-755.
APA	Hong W.,Fan JB.,Yuan CM.,Zhang C.,Hu YY.,...&yirufang@gmail.com.(2014).Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression.NEUROREPORT,25(10),753-755.
MLA	Hong W,et al."Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression".NEUROREPORT 25.10(2014):753-755.

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2014062301.pdf（198KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

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