| PATTERNED HIGH-FREQUENCY STIMULATION INDUCES A FORM OF LONG-TERM DEPRESSION DEPENDENT ON GABAA AND mACh RECEPTORS IN THE HIPPOCAMPUS | |
| Zhu YY1,2; Jing L1; Duan TT1,2; Yuan Q1; Cao J1; Zhou QX*1; Xu L*1,2; qixin_zhou@126.com; lxu@vip.163.com | |
| 2013 | |
| 发表期刊 | NEUROSCIENCE
 |
| 卷号 | 250期号:X页码:658-663 |
| 合作性质 | 其它 |
| 摘要 | Certain patterns of neural activity can induce N-methyl-D-aspartic acid receptor (NMDAR)-dependent synaptic plasticity, one of the important foundations of memory. Here, we report that a patterned high-frequency stimulation (PHS) induces rat hippocampal long-term depression (LTD) in an NMDAR-independent manner that requires coactivation of GABA(A)Rs and muscarinic acetylcholine receptors (mAChRs), and endocytosis of AMPARs. Thus, we disclose that a patterned high-frequency stimulation triggers GABAAR and mAChR-dependent LTD in the hippocampus |
| 关键词 | Hippocampal Ca1 Long-term Depression Gaba(a) Receptors Mach Receptors |
| 资助者 | This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). ; This work was sup- ported by 973 program from the Ministry of Science and Technology of China (2013CB835103 and 2009CB941302 to L.X., 2009CB522006 to J.C.), NSFC-CIHR Joint Grant (81168820536 to L.X.), National Natural Science Foundation of China (31100775 to Q.-X.Z.) and Strategic Priority Research Program of CAS (XDB0202 to L.X.). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/8014 |
| 专题 | 科研部门_学习记忆的分子神经机制（徐林） 科研部门_动物模型与人类重大疾病机理重点实验室 |
| 通讯作者 | qixin_zhou@126.com; lxu@vip.163.com |
| 作者单位 | 1.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Learning and Memory, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2.School of Life Sciences, University of Science and Technology of China, Hefei 230027, China |
| 推荐引用方式 GB/T 7714 | Zhu YY,Jing L,Duan TT,et al. PATTERNED HIGH-FREQUENCY STIMULATION INDUCES A FORM OF LONG-TERM DEPRESSION DEPENDENT ON GABAA AND mACh RECEPTORS IN THE HIPPOCAMPUS[J]. NEUROSCIENCE,2013,250(X):658-663. |
| APA | Zhu YY.,Jing L.,Duan TT.,Yuan Q.,Cao J.,...&lxu@vip.163.com.(2013).PATTERNED HIGH-FREQUENCY STIMULATION INDUCES A FORM OF LONG-TERM DEPRESSION DEPENDENT ON GABAA AND mACh RECEPTORS IN THE HIPPOCAMPUS.NEUROSCIENCE,250(X),658-663. |
| MLA | Zhu YY,et al."PATTERNED HIGH-FREQUENCY STIMULATION INDUCES A FORM OF LONG-TERM DEPRESSION DEPENDENT ON GABAA AND mACh RECEPTORS IN THE HIPPOCAMPUS".NEUROSCIENCE 250.X(2013):658-663. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 2014092616.pdf（947KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
| 个性服务 |
| 推荐该条目 |
| 保存到收藏夹 |
| 查看访问统计 |
| 导出为Endnote文件 |
| 谷歌学术 |
| 谷歌学术中相似的文章 |
| [Zhu YY]的文章 |
| [Jing L]的文章 |
| [Duan TT]的文章 |
| 百度学术 |
| 百度学术中相似的文章 |
| [Zhu YY]的文章 |
| [Jing L]的文章 |
| [Duan TT]的文章 |
| 必应学术 |
| 必应学术中相似的文章 |
| [Zhu YY]的文章 |
| [Jing L]的文章 |
| [Duan TT]的文章 |
| 相关权益政策 |
| 暂无数据 |
| 收藏/分享 |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论