Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors

	Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors
	Chai AP 1,2; Ma WP 1; Wang LP 1; Cao J 1; Xu L1 ; Yang YX1; Mao RR1; yangyx@mail.kiz.ac.cn ; talktomaomao@163.com
	2015
发表期刊	BRAIN RESEARCH
卷号	1622 期号:X 页码:72-80
合作性质	其它
摘要	Previous study reported that chronic constant light exposure caused hippocampus-dependent long-term memory deficit. However, the underlying cellular mechanism of this impairment is still unclear. Multiple lines of evidence indicated that long-term potentiation (LTP) is a cellular model for memory formation. Here we found that, by recording of field excitatory postsynaptic potential (fEPSP) in vitro, chronic constant light (CCL, 3 weeks) exposure impaired the late long-term potentiation (L-LTP), but not early long-term potentiation (E-LTP) and basal transmission in Schaffer collateral (SC)-CA1 synapses of hippocampal slices from rats. Because L-LTP depends on D1/D5 receptors, we examined whether interference of D1/D5 receptors can modulate L-LTP of CCL rats. Bath application of D1/D5 receptors antagonist SCH23390 (1μM) blocked L-LTP in control rats and attenuated the impaired L-LTP in CCL rats. In contrast, pre-incubation of D1/D5 receptors agonist SKF38393 (25μM) occluded further L-LTP in control rats while exacerbated the L-LTP impairment in CCL rats. These results suggested that CCL-induced L-LTP impairment can be modulated by D1/D5 receptors. Our findings may contribute to the further understanding of synaptic plasticity mechanism underlying hippocampal long-term memory impairment induced by circadian rhythm disruption.
关键词	Circadian Rhythm Disruption D1/d5 Receptors Hippocampus Long-term Potentiation
资助者	This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048).
收录类别	SCI
语种	英语
资助者	This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048). ; This work was supported by National Basic Program of China (2013CB835103), Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02020002), NSFC-CIHR Joint Grant (81161120536), National Natural Science Foundation of China (31100786, 81171294, U1032605 and U1132602), and Science and Technology Program of Yunnan Province (2013GA003 and 2013FA048).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/9372
专题	科研部门_学习记忆的分子神经机制（徐林）科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	yangyx@mail.kiz.ac.cn; talktomaomao@163.com
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms, KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Disease, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming 650223, China 2.Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming 650223, China
推荐引用方式 GB/T 7714	Chai AP,Ma WP,Wang LP,et al. Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors[J]. BRAIN RESEARCH,2015,1622(X):72-80.
APA	Chai AP.,Ma WP.,Wang LP.,Cao J.,Xu L.,...&talktomaomao@163.com.(2015).Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors.BRAIN RESEARCH,1622(X),72-80.
MLA	Chai AP,et al."Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors".BRAIN RESEARCH 1622.X(2015):72-80.

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