分子免疫药理学（郑永唐）知识库

QQ客服 官方微博 反馈留言

	Cloning, sequencing, and polymorphism analysis of novel classical MHC class I alleles in northern pig-tailed macaques (Macaca leonina)
	Lian XD1,2; Zhang XH1,2; Dai ZX1; Zheng YT*1; zhengyt@mail.kiz.ac.cn
	2016
发表期刊	IMMUNOGENETICS
卷号	68期号:4页码:261-274
合作性质	其它
摘要	The northern pig-tailed macaque (Macaca leonina) has been confirmed to be an independent species from the pig-tailed macaque group of Old World monkey. We have previously reported that the northern pig-tailed macaques were also susceptible to HIV-1. Here, to make this animal a potential HIV/AIDS model and to discover the mechanism of virus control, we attempted to assess the role of major histocompatibility complex (MHC) class I-restricted immune responses to HIV-1 infection, which was associated with viral replication and disease progression. As an initial step, we first cloned and characterized the classical MHC class I gene of northern pig-tailed macaques. In this study, we identified 39 MHC class I alleles including 17 MHC-A and 22 MHC-B alleles. Out of these identified alleles, 30 were novel and 9 were identical to alleles previously reported from other macaque species. The MHC-A and MHC-B loci were both duplicates as rhesus macaques and southern pig-tailed macaques. In addition, we also detected the patterns of positive selection in northern pig-tailed macaques and revealed the existence of balance selection with 20 positive selection sites in the peptide binding region. The analysis of B and F peptide binding pockets in northern and southern pig-tailed macaques and rhesus macaques suggested that they were likely to share a few common peptides to present. Thus, this study provides important MHC immunogenetics information and adds values to northern pig-tailed macaques as a promising HIV/AIDS model.
关键词	Aids Model Mhc Class i Macaca Leonina Northern Pig-tailed Macaque
资助者	This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan.
收录类别	SCI
语种	英语
资助者	This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan. ; This work was supported by the National Basic Research Program of China (2012CBA01305), the National Natural Science Foundation of China (81172876, 81373124, 81471620, 81571606), the Knowledge In- novation Program of CAS (KSCX2-EW-R-13, KJZD-EW-L10-02), the Natural Science Foundation of Yunnan Province (2014FB181), and the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan.
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/9532
专题	科研部门_分子免疫药理学（郑永唐） 科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	zhengyt@mail.kiz.ac.cn
作者单位	1.Chinese Acad Sci, Chinese Acad Sci & Yunnan Prov, Key Lab Anim Models & Human Dis Mech, Kunming Inst Zool, Kunming 650223, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Lian XD,Zhang XH,Dai ZX,et al. Cloning, sequencing, and polymorphism analysis of novel classical MHC class I alleles in northern pig-tailed macaques (Macaca leonina)[J]. IMMUNOGENETICS,2016,68(4):261-274.
APA	Lian XD,Zhang XH,Dai ZX,Zheng YT*,&zhengyt@mail.kiz.ac.cn.(2016).Cloning, sequencing, and polymorphism analysis of novel classical MHC class I alleles in northern pig-tailed macaques (Macaca leonina).IMMUNOGENETICS,68(4),261-274.
MLA	Lian XD,et al."Cloning, sequencing, and polymorphism analysis of novel classical MHC class I alleles in northern pig-tailed macaques (Macaca leonina)".IMMUNOGENETICS 68.4(2016):261-274.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
2016072019.pdf（1344KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

个性服务

推荐该条目

保存到收藏夹

查看访问统计

导出为Endnote文件

谷歌学术

谷歌学术中相似的文章

[Lian XD]的文章

[Zhang XH]的文章

[Dai ZX]的文章

百度学术

百度学术中相似的文章

[Lian XD]的文章

[Zhang XH]的文章

[Dai ZX]的文章

必应学术

必应学术中相似的文章

[Lian XD]的文章

[Zhang XH]的文章

[Dai ZX]的文章

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。