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	Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis
	Ye J*1,2; Nie WH1; Graphodatsky AS4; Yang F5; Wang J1; Su W1; Jing M3; yjpyyjjpp@hotmail.com
	2011
发表期刊	CYTOGENETIC AND GENOME RESEARCH
卷号	132期号:1-2页码:41-46
合作性质	其它
摘要	Comparative genomic data for ochotonids (pikas) are important for understanding the karyotype evolution of lagomorphs. Here, we have established the first genome-wide chromosomal homologies between human and the Forrest's pika (Ochotona forresti, 2n = 54) by cross-species chromosome painting. Integration of our map with the published comparative chromosome map between human and rabbit has enabled the establishment of an indirect homology map between Forrest's pika and domestic rabbit (Oryctolagus cuniculus, 2n = 44), representing the 2 Lagomorpha families: Leporidae and Ochotonidae. Our results demonstrate that (1) most of the proposed ancestral eutherian syntenies or syntenic associations have been retained in the O. forresti genome; (2) the HSA1/10p association, one of the 2 signature rearrangements that were proposed to support the grouping of the orders Lagomorpha and Rodentia into a monophyletic clade called Glires, is also present in the O. forresti genome; and (3) Robertsonian translocations have contributed to the karyotype differences between O. forresti and O. cuniculus.
关键词	Chromosome Painting Evolution Forrest's Pika Lagomorpha Mapping Rabbit
资助者	This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust.
收录类别	SCI
语种	英语
资助者	This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. ; This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust.
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/9604
专题	遗传资源与进化国家重点实验室_保护遗传学(细胞库) 遗传资源与进化国家重点实验室
通讯作者	yjpyyjjpp@hotmail.com
作者单位	1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming Yunnan 650223, China 2.College of Life Sciences, Shaoxing University, Shaoxing 3.College of Life Sciences, Ludong University, Yantai , PR China 4.Institute of Chemical Biology and Fundamental Medicine, Novosibirsk , Russia 5.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton
推荐引用方式 GB/T 7714	Ye J*,Nie WH,Graphodatsky AS,et al. Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis[J]. CYTOGENETIC AND GENOME RESEARCH,2011,132(1-2):41-46.
APA	Ye J*.,Nie WH.,Graphodatsky AS.,Yang F.,Wang J.,...&yjpyyjjpp@hotmail.com.(2011).Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis.CYTOGENETIC AND GENOME RESEARCH,132(1-2),41-46.
MLA	Ye J*,et al."Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis".CYTOGENETIC AND GENOME RESEARCH 132.1-2(2011):41-46.

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