Comparison of HIV-, HBV-, HCV- and Co-Infection Prevalence between Chinese and Burmese Intravenous Drug Users of the China-Myanmar Border Region

	Comparison of HIV-, HBV-, HCV- and Co-Infection Prevalence between Chinese and Burmese Intravenous Drug Users of the China-Myanmar Border Region
	Zhou YH 1,5; Liu F 1,5; Yao ZH 1,5; Duo L 2; Li H 3; Sun Y 1,4; Zheng YT*1; zhengyt@mail.kiz.ac.cn
	2011
发表期刊	PLOS ONE
卷号	6 期号:1 页码:e16349
合作性质	其它
摘要	Background: Co-infection with HIV and HCV and/or HBV is highly prevalent in intravenous drug users (IDUs). Because of the proximity to the "Golden Triangle'', HIV prevalence among the IDUs is very high in the China-Myanmar border region. However, there are few studies about co-infection with HIV and HCV and/or HBV, especially in the region that belongs to Myanmar. Methods: 721 IDUs, including 403 Chinese and 318 Burmese, were investigated for their HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) serological status. Statistical analysis was performed to evaluate the differences of the epidemic situation between the Chinese IDUs and the Burmese IDUs. Results: Among the Chinese IDUs and the Burmese IDUs, HCV infection was the most prevalent (69.0% vs 48.1%, P<0.001), followed by HBV (51.6% vs 43.1%, P<0.05) and HIV (33.7% vs 27.0%, P>0.05). Besides, there were more HIV-HBV co-infected IDUs (20.1% vs 11.3%, P<0.005), and HIV-HCV co-infected IDUs (31.8% vs 23.9%, P<0.05) in China than in Myanmar, as well as HIV-HBV-HCV triple infection (19.1% vs 10.4%, P<0.005). Conclusion: Co-infection with HIV and HCV and/or HBV is highly prevalent among the IDUs in the China-Myanmar border region. The HIV epidemic appears to be in a downward trend, compared with previous reports. However, all infections were more prevalent among the Chinese IDUs than among the Burmese.
资助者	This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program. ; This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program. ; This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program. ; This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program.
收录类别	SCI
语种	英语
资助者	This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program. ; This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program. ; This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program. ; This work was supported in part by grants from the National Basic Research Program of China (2006CB504302, 2009CB522306), the National Natural Science Foundation of China (30671960, U0832601), the Eleventh Five-Year Key Scientific and Technological Program of China (2009ZX10004-902, 2009ZX09501- 029, 2008ZX10001-002, 2008ZX10001-015), and the HIV/AIDS Asia Regional Program.
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/353002/6570
专题	科研部门_分子免疫药理学（郑永唐）科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	zhengyt@mail.kiz.ac.cn
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 2.The Second People’s Hospital of Yunnan Province, Kunming, China 3.Yunnan Center for Disease Control and Prevention, Kunming, China 4.The First People’s Hospital of Yunnan Province, Kunming, China 5.The Graduate School of the Chinese Academy of Sciences, Beijing, China
推荐引用方式 GB/T 7714	Zhou YH,Liu F,Yao ZH,et al. Comparison of HIV-, HBV-, HCV- and Co-Infection Prevalence between Chinese and Burmese Intravenous Drug Users of the China-Myanmar Border Region[J]. PLOS ONE,2011,6(1):e16349.
APA	Zhou YH.,Liu F.,Yao ZH.,Duo L.,Li H.,...&zhengyt@mail.kiz.ac.cn.(2011).Comparison of HIV-, HBV-, HCV- and Co-Infection Prevalence between Chinese and Burmese Intravenous Drug Users of the China-Myanmar Border Region.PLOS ONE,6(1),e16349.
MLA	Zhou YH,et al."Comparison of HIV-, HBV-, HCV- and Co-Infection Prevalence between Chinese and Burmese Intravenous Drug Users of the China-Myanmar Border Region".PLOS ONE 6.1(2011):e16349.

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