Comparative Chromosome Painting of Four Siberian Vespertilionidae Species with Aselliscus stoliczkanus and Human Probes
Kulemzina AI*1; Nie W2; Trifonov VA1; Staroselec Y1; Vasenkov DA3; Volleth M4; Yang F5; Graphodatsky AS1; zaka1@mcb.nsc.ru
2011
发表期刊CYTOGENETIC AND GENOME RESEARCH
卷号134期号:3页码:200-205
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摘要Vespertilionidae is the largest chiropteran family that comprises species of different specialization and wide geographic distribution. Up to now, only a few vespertilionid species have been studied by molecular cytogenetic approaches. Here, we have investigated the karyotypic relationships of 4 Vespertilionidae species from Siberia by G-banding and comparative chromosome painting. Painting probes from Aselliscus stoliczkanus were used to establish interspecific homologous chromosomal segments in Myotis dasycneme (2n = 44), Murina hilgendorfi (2n = 44), Plecotus auritus (2n = 32), and Vespertilio murinus (2n = 38). Robertsonian translocations and a few inversions differentiated the karyotypes of the examined species. Painting of P. auritus karyotype with human probes revealed 3 previously undetected cryptic segments homologous to human chromosomes (Homo sapiens, HSA) 8, 15, and 19, respectively. As a consequence, the existence of 2 HSA 4 + 8 syntenies in the P. auritus karyotype has been proven. In addition, a pericentric inversion or centromere shift was revealed on the smallest metacentric P. auritus chromosome 16/17 using the HSA 16 probe explaining the different G-banding pattern in comparison to the homologous Myotis chromosome 16/17.
关键词Chromosome Painting Robertsonian Translocation Vespertilionidae
收录类别SCI
语种英语
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/353002/6638
专题遗传资源与进化国家重点实验室_保护遗传学(细胞库)
遗传资源与进化国家重点实验室
通讯作者zaka1@mcb.nsc.ru
作者单位1.Molecular and Cellular Biology Department, Institute of Chemical Biology and Fundamental Medicine, SÐ’ RAS, Novosibirsk, Russia
2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P.R. China
3.Institute of Animal Ecology and Systematics, SÐ’ RAS, Novosibirsk, Russia
4.Department of Human Genetics, Otto von Guericke University Magdeburg, Magdeburg, Germany
5.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
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Kulemzina AI*,Nie W,Trifonov VA,et al. Comparative Chromosome Painting of Four Siberian Vespertilionidae Species with Aselliscus stoliczkanus and Human Probes[J]. CYTOGENETIC AND GENOME RESEARCH,2011,134(3):200-205.
APA Kulemzina AI*.,Nie W.,Trifonov VA.,Staroselec Y.,Vasenkov DA.,...&zaka1@mcb.nsc.ru.(2011).Comparative Chromosome Painting of Four Siberian Vespertilionidae Species with Aselliscus stoliczkanus and Human Probes.CYTOGENETIC AND GENOME RESEARCH,134(3),200-205.
MLA Kulemzina AI*,et al."Comparative Chromosome Painting of Four Siberian Vespertilionidae Species with Aselliscus stoliczkanus and Human Probes".CYTOGENETIC AND GENOME RESEARCH 134.3(2011):200-205.
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