| Phenols with Anti-HIV Activity from Daphne acutiloba | |
| Huang SZ1,4; Zhang XJ3,4; Li XY3,4; Jiang HZ1,4; Ma QY2; Wang PC1,4; Liu YQ1; Hu JM1; Zheng YT3; Zhou J*1; Zhao YX*1,2; jzhou@mail.kib.ac.cn; zhaoyx1011@163.com | |
| 2012 | |
| 发表期刊 | PLANTA MEDICA
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| 卷号 | 78期号:2页码:182-185 |
| 合作性质 | 其它 |
| 摘要 | The present paper describes the study of the phytochemical properties and anti-HIV activity of the phenolic isolates of the plateau medicinal plant Daphne acutiloba Rehd. (Thymelaeceae). Two new lignans named daphnenin (1) and daphnetone (2), along with 11 known ones, were isolated, and their structures were elucidated by 1D and 2D NMR spectroscopy as well as HR-E-SI-MS. In the anti-HIV activity study, daphnenin (1) and caffeic acid n-octadecyl ester (13) showed definite anti-HIV activity with EC50 values of 0.39 and 0.16 mu g/mL, respectively. |
| 关键词 | Daphne Acutiloba Thymelaeceae Anti-hiv Activity Phenols |
| 资助者 | This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). ; This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). ; This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). ; This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). ; This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). ; This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). ; This work was financially supported by the National Nonprofit Institute Research Grant of CATAS-ITBB (No.110301) and Natural Science Foundation of Yunnan (2008CD159). |
| WOS记录号 | WOS:000299909300014 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/353002/6892 |
| 专题 | 科研部门_分子免疫药理学(郑永唐) |
| 通讯作者 | jzhou@mail.kib.ac.cn; zhaoyx1011@163.com |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Peopleʼs Republic of China 2.Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Peopleʼs Republic of China 3.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Peopleʼs Republic of China 4.Graduate School of the Chinese Academy of Sciences, Beijing, Peopleʼs Republic of China |
| 推荐引用方式 GB/T 7714 | Huang SZ,Zhang XJ,Li XY,et al. Phenols with Anti-HIV Activity from Daphne acutiloba[J]. PLANTA MEDICA,2012,78(2):182-185. |
| APA | Huang SZ.,Zhang XJ.,Li XY.,Jiang HZ.,Ma QY.,...&zhaoyx1011@163.com.(2012).Phenols with Anti-HIV Activity from Daphne acutiloba.PLANTA MEDICA,78(2),182-185. |
| MLA | Huang SZ,et al."Phenols with Anti-HIV Activity from Daphne acutiloba".PLANTA MEDICA 78.2(2012):182-185. |
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