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Discovery of ZFD-10 of a pyridazino[4,5-b]indol-4(5H)-one derivative as an anti-ZIKV agent and a ZIKV NS5 RdRp inhibitor 期刊论文
ANTIVIRAL RESEARCH, 2023, 卷号: 214
作者:  Zhou, GF;  Qian, WY;  Li, F;  Yang, RH;  Wang, N;  Zheng, CB;  Li, CY;  Gu, XR;  Yang, LM;  Liu, JS;  Xiong, SD;  Zhou, GC;  Zheng, YT
Adobe PDF(4577Kb)  |  收藏  |  浏览/下载：22/0  |  提交时间：2024/06/21
Antiviral effects of the fused tricyclic derivatives of indoline and imidazolidinone on ZIKV infection and RdRp activities of ZIKV and DENV 期刊论文
VIRUS RESEARCH, 2023, 卷号: 326
作者:  Zhou, GF;  Li, F;  Xue, JX;  Qian, WY;  Gu, XR;  Zheng, CB;  Li, CY;  Yang, LM;  Xiong, SD;  Zhou, GC;  Zheng, YT
Adobe PDF(6189Kb)  |  收藏  |  浏览/下载：94/0  |  提交时间：2024/06/21
Design, synthesis, discovery and SAR of the fused tricyclic derivatives of indoline and imidazolidinone against DENV replication and infection 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 120
作者:  Qian, WY;  Xue, JX;  Xu, JX;  Li, F;  Zhou, GF;  Wang, F;  Luo, RH;  Liu, JS;  Zheng, YT;  Zhou, GC
Adobe PDF(5411Kb)  |  收藏  |  浏览/下载：1148/0  |  提交时间：2023/04/18
Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:  Qian, WY;  Zhou, GF;  Ge, XT;  Xue, JX;  Zheng, CB;  Yang, LM;  Gu, XR;  Li, CY;  Xiong, SD;  Zheng, YT;  Zhou, GC
Adobe PDF(4648Kb)  |  收藏  |  浏览/下载：48/0  |  提交时间：2023/04/18
Ultrasensitive tumour-agnostic non-invasive detection of colorectal cancer recurrence using ctDNA methylation 期刊论文
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 9
作者:  Xiao, Y;  Wang, XD;  Weng, H;  Ding, Z;  Qian, KY;  Jin, W;  Lu, S;  Ju, LG;  He, ZW;  Wang, G;  Xie, XY;  Liu, DM;  Fan, Z;  Wu, K;  Li, S;  Guo, HH;  Qian, GF;  Jiang, W;  Leng, YJ;  Zhao, JP;  Cao, XY;  Peng, MS;  Jiang, CQ;  Li, L;  Zhang, Y;  Wang, XH
Adobe PDF(1327Kb)  |  收藏  |  浏览/下载：1447/0  |  提交时间：2023/04/12
Pharmacokinetics of sifuvirtide, a novel anti-HIV-1 peptide, in monkeys and its inhibitory concentration in vitro 期刊论文
ACTA PHARMACOLOGICA SINICA, 2005, 卷号: 26, 期号: 10, 页码: 1274-1280
作者:  Dai SJ;  Dou GF;  Qian XH*;  Song HF*;  Tang ZM;  Liu DS;  Liu XW;  Yang LM;  Zheng YT;  Liang Q;  qianxh@nic.bmi.ac.cn;  songhf@nic.bmi.ac.cn
Adobe PDF(528Kb)  |  收藏  |  浏览/下载：207/2  |  提交时间：2010/08/24
Sifuvirtide  Hiv Fusion Inhibitors  Pharmacokinetics  Hiv  Enfuvirtide  On-line Solid-phase Extraction  Macaque