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阿尔茨海默病风险基因功能鉴定及潜在药物靶点研究 学位论文
理学博士, 北京: 中国科学院大学, 2019
作者:  罗荣灿
Adobe PDF(8694Kb)  |  收藏  |  浏览/下载:455/0  |  提交时间:2020/12/17
阿尔茨海默病,Serpinf1,Pparα,吉非罗齐,匹立尼酸  alzheimer’s Disease, Serpinf1, Pparα, Gemfibrozil, Wy14643  
利用转录组数据探究老年复杂性疾病 学位论文
理学博士, 北京: 中国科学院大学, 2019
作者:  郑俊娟
Adobe PDF(9470Kb)  |  收藏  |  浏览/下载:3553/0  |  提交时间:2020/12/17
基因的差异表达,阿茨海默症,中风,基因共表达网络,中草药植物  differential Expression Of Genes, Alzheimer's Disease, Stroke, Gene co-Expression Network, Herbal Plant  
中国长寿人群健康长寿保护性机制研究 学位论文
理学博士, 北京: 中国科学院大学, 2018
作者:  刘耀文
Adobe PDF(5071Kb)  |  收藏  |  浏览/下载:132/0  |  提交时间:2020/12/15
衰老,老年性疾病,长寿,转录组,阿尔茨海默病  aging, Senile Diseases, Longevity, Transcriptome, Alzheimer's Disease  
利用转录组数据探究人类复杂疾病 学位论文
理学博士, 北京: 中国科学院大学, 2018
作者:  王倩
Adobe PDF(2732Kb)  |  收藏  |  浏览/下载:3393/0  |  提交时间:2020/12/15
转录组整合分析,帕金森病,阿茨海默症,癌症总生存期,T细胞受体信号通路  transcriptome Integrative Analysis, Parkinson's Disease, Alzheimer's Disease, Cancer Overall Survival, t Cell Receptor Signaling Pathway  
A pleiotropic effect of the APOE gene: association of APOE polymorphisms with multibacillary leprosy in Han Chinese from Southwest China 期刊论文
British Jouranl Dermatology, 2018, 卷号: **, 期号: **, 页码: Epub ahead of print
作者:  Wang D*;  Zhang DF;  Wu Y;  Yu XF;  Long H;  Li YY;  Yao YG*;  Li GD;  Bi R;  Fan Y;  yaoyg@mail.kiz.ac.cn;  wangdong@mail.kiz.ac.cn
Adobe PDF(1137Kb)  |  收藏  |  浏览/下载:1117/0  |  提交时间:2017/10/10
Apoe  Alzheimer's Disease  Genetic Susceptibility  Leprosy  Lipid  
Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer's Disease Research? 期刊论文
Journal of Alzheimer’s Disease, 2018, 期号: 61, 页码: 1015–1028
作者:  Yu Fan;  Yong-Gang Yao;  Ling-Yan Su;  Qun Xiang;  Dandan Yu;  Ling Xu;  Jia-Qi Chen;  Rui Bi;  Dong-Dong Wu;  Ping Zheng
Adobe PDF(2165Kb)  |  收藏  |  浏览/下载:174/0  |  提交时间:2018/09/19
Ad Pathway  Alzheimer’s Disease  Animal Model  Chinese Tree Shrews  Mrna Expression Profiling  
A systematic integrated analysis of brain expression profiles reveals YAP1 and other prioritized hub genes as important upstream regulators in Alzheimer’s disease 期刊论文
Alzheimer's & Dementia, 2018, 期号: 14, 页码: 215-229
作者:  Min Xu;  zhang DF;  Rongcan Luo;  Yong Wu;  Hejiang Zhou;  Li-Li Kong;  Rui Bi;  Yong-Gang Yao
Adobe PDF(4095Kb)  |  收藏  |  浏览/下载:1156/0  |  提交时间:2018/09/28
Alzheimer’s Disease  Differential Expression  Convergent Functional Genomic  Upstream Regulator  Database  
A strategy to find novel candidate anti-Alzheimer's disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants. 期刊论文
PeerJ, 2018, 期号: ~, 页码: 4756
作者:  Bi-Wen Chen;  Jing-Fei Huang;  Guang-Hui Wang;  Gong-Hua Li;  Jia-Qian Liu;  Jun-Juan Zheng;  Qian Wang;  Hui-Juan Li;  Shao-Xing Dai
Adobe PDF(11563Kb)  |  收藏  |  浏览/下载:60/0  |  提交时间:2018/09/19
Alzheimer’s Disease  Molecular Docking  Candidate Drugs  
A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants 期刊论文
PeerJ, 2018, 期号: 6, 页码: e4756
作者:  Bi-Wen Chen;  Jing-Fei Huang;  Guang-Hui Wang;  Gong-Hua Li;  Jia-Qian Liu;  Jun-Juan Zheng;  Qian Wang;  Hui-Juan Li;  Shao-Xing Dai
Adobe PDF(11563Kb)  |  收藏  |  浏览/下载:3423/0  |  提交时间:2018/09/29
Alzheimer’s Disease  Molecular Docking  Candidate Drugs  
建立新型非人灵长类脑区转基因动物模型的关键技术与方法的研发和应用 学位论文
理学博士, 北京: 中国科学院大学, 2017
作者:  吴诗昊
Adobe PDF(10139Kb)  |  收藏  |  浏览/下载:83/0  |  提交时间:2019/09/11
非人灵长类,转基因动物模型,阿尔兹海默病,帕金森氏综合征,Rett综合症  Non-human Primates,transgenetic Animal Model,parkinson’s Disease, Alzheimer’s Disease, Rett Syndrome