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14-Formyl-15-aryloxy/methoxymatrine and 14-Aryloxymethylidenyl-mat- rine Derivatives as Anti-HIV-1 Agents 期刊论文
Medicinal Chemistry, 2018, 期号: 14, 页码: 249-252
作者:  Jiulin Huang;  Liu-Meng Yang;  Yuanyuan Zhang;  Yong-Tang Zheng;  Hui Xu
Adobe PDF(1024Kb)  |  收藏  |  浏览/下载：54/0  |  提交时间：2018/09/20
Matrine Derivatives  Aids  Hiv-1  Inhibitors  Antiretroviral Drugs  Peptide Drugs  Matrines  
Design, synthesis and anti-HIV-1 evaluation of hydrazide-based peptidomimetics as selective gelatinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 9, 页码: 2125-2136
作者:  Yang L;  Wang P;  Pang W;  Li YG;  Shen YM;  Zheng YT*;  Li X*;  Wu JF;  Yang LM;  Wang RR;  zhengyt@mail.kiz.ac.cn;  tjulx2004@sdu.edu.cn
Adobe PDF(3521Kb)  |  收藏  |  浏览/下载：121/4  |  提交时间：2016/04/05
Hydrazide Derivatives  Quinoxalinone  Selective Gelatinase Inhibitors  Peptidomimetics  Anti-hiv Activity  
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 12, 页码: 3146-3158
作者:  Li BW;  Zhang FH;  Serrao E;  Chen H;  Sanchez TW;  Yang LM;  Neamati N;  Zheng YT;  Wang H*;  Long YQ*;  huiwang@scnu.edu.cn;  yqlong@mail.shcnc.ac.cn
Adobe PDF(1380Kb)  |  收藏  |  浏览/下载：322/2  |  提交时间：2014/10/15
Chelation  Strand Transfer  Ledgf/p75  Hiv-1 Integrase Inhibitors  Flavonoid  
Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8852-8857
作者:  Tang JJ;  Zhang L;  Jiang LP;  Di L;  Yan YM;  Tu ZC*;  Yang CP;  Zuo ZL;  Hou B;  Xia HL;  Chen YB*;  Cheng YX*;  tu_zhengchao@gibh.ac.cn;  ybchen@mail.kiz.ac.cn;  yxcheng@mail.kib.ac.cn
Adobe PDF(678Kb)  |  收藏  |  浏览/下载：134/3  |  提交时间：2014/12/05
Polyrhachis Dives  Dopamine Derivative  Rock1/2 Inhibitors  Nscs  
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 5, 页码: 1976-1979
作者:  Yan JW;  Huang N;  Li SK;  Yang LM;  Xing WQ;  Zheng YT*;  Hu YH*;  zhengyt@mail.kiz.ac.cn;  yhhu@mail.shcnc.ac.cn
Adobe PDF(409Kb)  |  收藏  |  浏览/下载：163/5  |  提交时间：2012/03/19
Hiv-1 Protease Inhibitors  Amprenavir  Darunavir Biaryl Compounds  Docking Study  
Pharmacokinetics of sifuvirtide, a novel anti-HIV-1 peptide, in monkeys and its inhibitory concentration in vitro 期刊论文
ACTA PHARMACOLOGICA SINICA, 2005, 卷号: 26, 期号: 10, 页码: 1274-1280
作者:  Dai SJ;  Dou GF;  Qian XH*;  Song HF*;  Tang ZM;  Liu DS;  Liu XW;  Yang LM;  Zheng YT;  Liang Q;  qianxh@nic.bmi.ac.cn;  songhf@nic.bmi.ac.cn
Adobe PDF(528Kb)  |  收藏  |  浏览/下载：201/2  |  提交时间：2010/08/24
Sifuvirtide  Hiv Fusion Inhibitors  Pharmacokinetics  Hiv  Enfuvirtide  On-line Solid-phase Extraction  Macaque