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RNF126 as a biomarker of a poor prognosis in invasive breast cancer and CHK1 inhibitor efficacy in breast cancer cells 期刊论文
Clinical Cancer Research, 2018, 卷号: 24, 期号: 7, 页码: 1629-1643
作者:  Xiaosong Yang;  Junran Zhang;  Zhaojun Qiu;  Zhanwen Du;  Yao Zhang;  Pengyan Fa;  Shashank Gorityala;  Shanhuai Ma;  Shunqiang Li;  Ceshi Chen;  Hongbing Wang;  Yan Xu;  Chunhong Yan;  Keri Ruth;  Zhefu Ma
Adobe PDF(2738Kb)  |  收藏  |  浏览/下载:75/0  |  提交时间:2018/09/28
Rnf126  Chk1  Replication Stress  Breast Cancer  Target Therapy  
Comprehensive integrated analysis of gene expression datasets identifies key anti-cancer targets in different stages of breast cancer. 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 期号: 16, 页码: 802-810
作者:  MENG-TING GONG;  WEN-XING LI;  WEN-WEN LV;  KAN HE
Adobe PDF(1790Kb)  |  收藏  |  浏览/下载:51/0  |  提交时间:2018/09/20
Breast Cancer  Gene Expression  Ribonucleotide Reductase Regulatory Subunit M2  Network  Target Genes  
环肽对脂代谢信号通路调控机制的研究 学位论文
理学硕士, 北京: 中国科学院大学, 2017
作者:  杜加诚
Adobe PDF(2862Kb)  |  收藏  |  浏览/下载:426/0  |  提交时间:2019/09/24
Srebp-1a,脂代谢,Ra-v,靶蛋白  Srebp-1a, Lipid Metabolism, Ra- v, Target Protein  
中草药抗中风活性化合物的发掘及分子机制研究 学位论文
理 学 博 士, 北京: 中国科学院大学, 2017
作者:  刘家倩
Adobe PDF(41289Kb)  |  收藏  |  浏览/下载:3459/3  |  提交时间:2019/09/09
抗中风,治疗靶点,传统中草药化合物,分子机制  Anti-stroke, Therapeutic Target, Traditional Chinese Medicinal Compounds, Molecular Mechanism  
Proteome-wide prediction of targets for aspirin: new insight into the molecular mechanism of aspirin 期刊论文
PEERJ, 2016, 卷号: 4, 期号: X, 页码: e1791
作者:  Dai SX;  Li WX;  Li GH*;  Huang JF*;  ligonghua@mail.kiz.ac.cn;  huangjf@mail.kiz.ac.cn
Adobe PDF(13013Kb)  |  收藏  |  浏览/下载:240/7  |  提交时间:2016/03/21
Aspirin  Binding Site  Cancer  Cardiovascular Disease  Molecular Docking  Target  
Integrated analysis of ischemic stroke datasets revealed sex and age difference in anti-stroke targets 期刊论文
PeerJ, 2016, 卷号: 4, 期号: X, 页码: e2470
作者:  Li WX;  Dai SX;  Zheng JJ;  Liu JQ;  Liu DH*;  Li GH*;  Huang JF*;  Wang Q;  Guo YC;  Hong Y;  seansean2014@126.com;  ligonghua@mail.kiz.ac.cn;  huangjf@mail.kiz.ac.cn
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载:1439/2  |  提交时间:2017/03/13
Anti-stroke Target  Sex And Age Difference  Ischemic Stroke  
Targeting the orexinergic system: Mainly but not only for sleep-wakefulness therapies 期刊论文
Alexandria Journal of Medicine, 2015, 卷号: 51, 期号: X, 页码: 279–286
作者:  Ghanemi A*;  Hu XT;  ghanemiabdelaziz@hotmail.com
Adobe PDF(615Kb)  |  收藏  |  浏览/下载:116/0  |  提交时间:2017/03/15
Orexin Receptors  Sleep-wakefulness Therapy  Potential Target  
Elements toward novel therapeutic targeting of the adrenergic system 期刊论文
NEUROPEPTIDES, 2015, 卷号: 49, 期号: X, 页码: 25-35
作者:  Ghanemi A*;  Hu XT;  ghanemiabdelaziz@hotmail.com
Adobe PDF(488Kb)  |  收藏  |  浏览/下载:115/5  |  提交时间:2015/04/10
Adrenergic System  Therapeutic Potential  Pharmacological Target  Gpcr  
mRNA expression and DNA methylation in three key genes involved in caste differentiation in female honeybees (Apis mellifera) 期刊论文
Zoological Research, 2014, 卷号: 35, 期号: 2, 页码: 92−98
作者:  Shao XL;  He SY;  Zhuang XY;  Fan Y;  Li YH*;  Yao YG;  liyh85@aliyun.com
Adobe PDF(780Kb)  |  收藏  |  浏览/下载:747/1  |  提交时间:2014/03/19
Caste Differentiation  Dna Methylation  Dna Methyltransferase 3  Honeybee  Target Of Rapamycin  
Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception 期刊论文
GENE, 2005, 卷号: 352, 期号: X, 页码: 30-35
作者:  Yang S;  Liu Y;  Su B*;  Lin AA;  Cavalli-Sforza LL;  Zhao ZM
Adobe PDF(230Kb)  |  收藏  |  浏览/下载:72/2  |  提交时间:2016/04/05
Gpcrs  Human-specific Substitution  Darwinian Positive Selection  Drug Target