| Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54 | |
| Wang LD*1,2; Zhou FY2,3; Li XM2,4; Sun LD5; Song X1,2; Jin Y1; Li JM1,2; Kong QP; Cai ZM; Zhang XJ5; ldwang@xxmu.edu.cn | |
| 2010 | |
| 发表期刊 | NATURE GENETICS
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| 卷号 | 42期号:9页码:759-U46 |
| 合作性质 | 其它 |
| 摘要 | We performed a genome-wide association study of esophageal squamous cell carcinoma (ESCC) by genotyping 1,077 individuals with ESCC and 1,733 control subjects of Chinese Han descent. We selected 18 promising SNPs for replication in an additional 7,673 cases of ESCC and 11,013 control subjects of Chinese Han descent and 303 cases of ESCC and 537 control subjects of Chinese Uygur-Kazakh descent. We identified two previously unknown susceptibility loci for ESCC: PLCE1 at 10q23 (P(Han combined) (for ESCC) = 7.46 x 10(-56), odds ratio (OR) = 1.43; P(Uygur-Kazakh for ESCC) = 5.70 x 10(-4), OR = 1.53) and C20orf54 at 20p13 (P(Han combined) (for ESCC) = 1.21 x 10(-11), OR = 0.86; P(Uygur-Kazakh for ESCC) = 7.88 x 10(-3), OR = 0.66). We also confirmed association in 2,766 cases of gastric cardia adenocarcinoma cases and the same 11,013 control subjects (PLCE1, P(Han for GCA) = 1.74 x 10(-39), OR = 1.55 and C20orf54, P(Han for GCA) = 3.02 x 10(-3), OR = 0.91). PLCE1 and C20orf54 have important biological implications for both ESCC and GCA. PLCE1 might regulate cell growth, differentiation, apoptosis and angiogenesis. C20orf54 is responsible for transporting riboflavin, and deficiency of riboflavin has been documented as a risk factor for ESCC and GCA. |
| 资助者 | Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). ; Supported by Xinxiang Medical University Key Scientific Program (2009-5), the National Natural Science Foundations (30670956, 30971133), 863 HighTech Key Projects (2006AA02A403, 2007AA02Z161), China Key Program on Basic Research (2007CB516812), Special Scientific Programs from Science and Technology Department (2009-8), Health Department (2009-10) and Education Department (2008-7) of Henan Province and Anhui Provincial Special Scientific Program (2007-7). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/10450 |
| 专题 | 科研部门_分子人类学（孔庆鹏） |
| 通讯作者 | ldwang@xxmu.edu.cn |
| 作者单位 | 1.Cancer Research Center, Xinxiang Medical University, Xinxiang, Henan, Chin 2.Henan Key Laboratory for Esophageal Cancer Research, Department of Basic Oncology and Pathology at College of Medicine, The First and The Second Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, China 3.Department of Thoracic Surgery and Tumor Prevention Treatment, Anyang Tumor Hospital, Anyang, Henan, China 4.Henan Prov Peoples Hosp, Dept Gastroenterol, Zhengzhou, Henan, Peoples R China 5.Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, China, Hefei, Anhui, China 6.Department of Pathology and Thoracic Surgery, Linzhou Esophageal Cancer Hospital, Linzhou, Henan, China 7.Department of Thoracic Surgery, Tumor Hospital of Linzhou, Linzhou, Henan, China. 8.Department of Thoracic Surgery, People’s Hospital and Chinese Medicine Hospital of Linzhou, Linzhou, Henan, China 9.Department of Thoracic Surgery and Radiotherapy, Cancer Hospital of Henan Province, Zhengzhou, Henan, China 10.Institute of Hematologic Disease and Department of Pathology, Changzhi Medical University, Changzhi, Shanxi, China 11.Department of Gastroenterology, Henan Provincial People’s Hospital, Zhengzhou, Henan, China 12.Department of Thoracic Surgery and Medical Research Center, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, China 13.Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China 14.Department of Nephrology, Huaihe Hospital, Henan University, Kaifeng, Henan, China 15.Department of Oncology, Xinyang Central Hospital, Xinyang, Henan, China 16.Department of Gastroenterology, Beijing Tongren Hospital Affiliated to Capital Medical University, Beijing, China 17.Department of Oncology, The First Affiliated Hospital of Nanyang Medical College, Nanyang, Henan, China 18.Department of Oncology, People’s Hospital of Puyang, Puyang, Henan, China 19.Department of Gastroenterology and Thoracic Surgery, The First People’s Hospital of Shangqiu, Shangqiu, Henan, China 20.Department of Gastroenterology, The Third People’s Hospital of Yunnan Province, Kunming, Yunnan, China |
| 推荐引用方式 GB/T 7714 | Wang LD*,Zhou FY,Li XM,et al. Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54[J]. NATURE GENETICS,2010,42(9):759-U46. |
| APA | Wang LD*.,Zhou FY.,Li XM.,Sun LD.,Song X.,...&ldwang@xxmu.edu.cn.(2010).Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.NATURE GENETICS,42(9),759-U46. |
| MLA | Wang LD*,et al."Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54".NATURE GENETICS 42.9(2010):759-U46. |
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