Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes

KIZ OpenIR > 科研部门 > 比较基因组学（宿兵）

	Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes
	Sun, Ting; Shen, Jiafei; Achilli, Alessandro; Chen, Ningbo; Chen, Qiuming; Dang, Ruihua; Zheng, Zhuqing; Zhang, Hucai; Zhang, Xiaoming; Wang, Shaoqiang; Zhang, Tao; Lu, Hongzhao; Ma, Yun; Jia, Yutang; Capodiferro, Marco Rosario; Huang, Yongzhen; Lan, Xianyong; Chen, Hong; Jiang, Yu; Lei, Chuzhao
	2020
发表期刊	GIGASCIENCE
ISSN	2047-217X
卷号	9 期号:2
摘要	Background: The domestic buffalo (Bubalus bubalis) is an essential farm animal in tropical and subtropical regions, whose genomic diversity is yet to be fully discovered. Results: In this study, we describe the demographic events and selective pressures of buffalo by analyzing 121 whole genomes (98 newly reported) from 25 swamp and river buffalo breeds. Both uniparental and biparental markers were investigated to provide the final scenario. The ancestors of swamp and river buffalo diverged similar to 0.23 million years ago and then experienced independent demographic histories. They were domesticated in different regions, the swamp buffalo at the border between southwest China and southeast Asia, while the river buffalo in south Asia. The domestic stocks migrated to other regions and further differentiated, as testified by (at least) 2 ancestral components identified in each subspecies. Different signals of selective pressures were also detected in these 2 types of buffalo. The swamp buffalo, historically used as a draft animal, shows selection signatures in genes associated with the nervous system, while in river dairy breeds, genes under selection are related to heat stress and immunity. Conclusions: Our findings substantially expand the catalogue of genetic variants in buffalo and reveal new insights into the evolutionary history and distinct selective pressures in river and swamp buffalo.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12790
专题	科研部门_比较基因组学（宿兵）
推荐引用方式 GB/T 7714	Sun, Ting,Shen, Jiafei,Achilli, Alessandro,et al. Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes[J]. GIGASCIENCE,2020,9(2).
APA	Sun, Ting.,Shen, Jiafei.,Achilli, Alessandro.,Chen, Ningbo.,Chen, Qiuming.,...&Lei, Chuzhao.(2020).Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes.GIGASCIENCE,9(2).
MLA	Sun, Ting,et al."Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes".GIGASCIENCE 9.2(2020).

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2021110304.pdf（6090KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文