The role of E3 ubiquitin ligase HECTD3 in cancer and beyond

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	The role of E3 ubiquitin ligase HECTD3 in cancer and beyond
	Jiang, QY; Li, FB; Cheng, Z; Kong, YJ; Chen, CS
	2020
发表期刊	CELLULAR AND MOLECULAR LIFE SCIENCES
ISSN	1420-682X
卷号	77 期号:8 页码:1483-1495
摘要	Ubiquitin modification plays significant roles in protein fate determination, signaling transduction, and cellular processes. Over the past 2 decades, the number of studies on ubiquitination has demonstrated explosive growth. E3 ubiquitin ligases are the key enzymes that determine the substrate specificity and are involved in cancer. Several recent studies shed light on the functions and mechanisms of HECTD3 E3 ubiquitin ligase. This review describes the progress in the recent studies of HECTD3 in cancer and other diseases. We propose that HECTD3 is a potential biomarker and a therapeutic target, and discuss the future directions for HECTD3 investigations.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12983
专题	科研部门_肿瘤生物学（陈策实）
推荐引用方式 GB/T 7714	Jiang, QY,Li, FB,Cheng, Z,et al. The role of E3 ubiquitin ligase HECTD3 in cancer and beyond[J]. CELLULAR AND MOLECULAR LIFE SCIENCES,2020,77(8):1483-1495.
APA	Jiang, QY,Li, FB,Cheng, Z,Kong, YJ,&Chen, CS.(2020).The role of E3 ubiquitin ligase HECTD3 in cancer and beyond.CELLULAR AND MOLECULAR LIFE SCIENCES,77(8),1483-1495.
MLA	Jiang, QY,et al."The role of E3 ubiquitin ligase HECTD3 in cancer and beyond".CELLULAR AND MOLECULAR LIFE SCIENCES 77.8(2020):1483-1495.

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