African Suid Genomes Provide Insights into the Local Adaptation to Diverse African Environments

	African Suid Genomes Provide Insights into the Local Adaptation to Diverse African Environments
	Xie, HB; Yan, C; Adeola, AC; Wang, K; Huang, CP; Xu, MM; Qiu, Q; Yin, X; Fan, CY; Ma, YF; Yin, TT; Gao, Y; Deng, JK; Okeyoyin, AO; Oluwole, OO; Omotosho, O; Okoro, VMO; Omitogun, OG; Dawuda, PM; Olaogun, SC; Nneji, LM; Ayoola, AO; Sanke, OJ; Luka, PD; Okoth, E; Lekolool, I; Mijele, D; Bishop, RP; Han, JL; Wang, W; Peng, MS; Zhang, YP
	2022
发表期刊	MOLECULAR BIOLOGY AND EVOLUTION
ISSN	0737-4038
卷号	39 期号:12
摘要	African wild suids consist of several endemic species that represent ancient members of the family Suidae and have colonized diverse habitats on the African continent. However, limited genomic resources for African wild suids hinder our understanding of their evolution and genetic diversity. In this study, we assembled high-quality genomes of a common warthog (Phacochoerus africanus), a red river hog (Potamochoerus porcus), as well as an East Asian Diannan small-ear pig (Sus scrofa). Phylogenetic analysis showed that common warthog and red river hog diverged from their common ancestor around the Miocene/Pliocene boundary, putatively predating their entry into Africa. We detected species-specific selective signals associated with sensory perception and interferon signaling pathways in common warthog and red river hog, respectively, which contributed to their local adaptation to savannah and tropical rainforest environments, respectively. The structural variation and evolving signals in genes involved in T-cell immunity, viral infection, and lymphoid development were identified in their ancestral lineage. Our results provide new insights into the evolutionary histories and divergent genetic adaptations of African suids.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13411
专题	科研部门_分子进化与基因组多样性（张亚平）
推荐引用方式 GB/T 7714	Xie, HB,Yan, C,Adeola, AC,et al. African Suid Genomes Provide Insights into the Local Adaptation to Diverse African Environments[J]. MOLECULAR BIOLOGY AND EVOLUTION,2022,39(12).
APA	Xie, HB.,Yan, C.,Adeola, AC.,Wang, K.,Huang, CP.,...&Zhang, YP.(2022).African Suid Genomes Provide Insights into the Local Adaptation to Diverse African Environments.MOLECULAR BIOLOGY AND EVOLUTION,39(12).
MLA	Xie, HB,et al."African Suid Genomes Provide Insights into the Local Adaptation to Diverse African Environments".MOLECULAR BIOLOGY AND EVOLUTION 39.12(2022).

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
2023031546.pdf（8085KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文