Hologenomic insights into mammalian adaptations to myrmecophagy

	Hologenomic insights into mammalian adaptations to myrmecophagy
	Cheng, SC; Liu, CB; Yao, XQ; Hu, JY; Yin, TT; Lim, BK; Chen, W; Wang, GD; Zhang, CL; Irwin, DM; Zhang, ZG; Zhang, YP; Yu, L
	2023
发表期刊	NATIONAL SCIENCE REVIEW
ISSN	2095-5138
卷号	10 期号:4
摘要	Highly specialized myrmecophagy (ant- and termite-eating) has independently evolved multiple times in species of various mammalian orders and represents a textbook example of phenotypic evolutionary convergence. We explored the mechanisms involved in this unique dietary adaptation and convergence through multi-omic analyses, including analyses of host genomes and transcriptomes, as well as gut metagenomes, in combination with validating assays of key enzymes' activities, in the species of three mammalian orders (anteaters, echidnas and pangolins of the orders Xenarthra, Monotremata and Pholidota, respectively) and their relatives. We demonstrate the complex and diverse interactions between hosts and their symbiotic microbiota that have provided adaptive solutions for nutritional and detoxification challenges associated with high levels of protein and lipid metabolisms, trehalose degradation, and toxic substance detoxification. Interestingly, we also reveal their spatially complementary cooperation involved in degradation of ants' and termites' chitin exoskeletons. This study contributes new insights into the dietary evolution of mammals and the mechanisms involved in the coordination of physiological functions by animal hosts and their gut commensals.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14001
专题	科研部门_分子进化与基因组多样性（张亚平）
推荐引用方式 GB/T 7714	Cheng, SC,Liu, CB,Yao, XQ,et al. Hologenomic insights into mammalian adaptations to myrmecophagy[J]. NATIONAL SCIENCE REVIEW,2023,10(4).
APA	Cheng, SC.,Liu, CB.,Yao, XQ.,Hu, JY.,Yin, TT.,...&Yu, L.(2023).Hologenomic insights into mammalian adaptations to myrmecophagy.NATIONAL SCIENCE REVIEW,10(4).
MLA	Cheng, SC,et al."Hologenomic insights into mammalian adaptations to myrmecophagy".NATIONAL SCIENCE REVIEW 10.4(2023).

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