A chromosome-scale reference genome of the Banna miniature inbred pig

	A chromosome-scale reference genome of the Banna miniature inbred pig
	Chen, HM; Xu, KX; Yan, C; Zhao, H; Jiao, DL; Si, S; Liu, ZX; Peng, GY; Jamal, MA; Lv, MJ; Wang, P; Zeng, YZ; Zhao, HY; Wang, MS; Wei, HJ
	2024
发表期刊	SCIENTIFIC DATA
卷号	11 期号:1
摘要	The Banna miniature inbred pig (BN) is an intensively inbred line for biomedical research and xenotransplantation due to its low individual variation and stable genetic background. Although it is originated from the Diannan miniature pig (DN), substantial genetic changes have actually occurred. However, the lack of a BN reference genome has limited studies on the complete genomic architecture and utilization as a biomedical model. Here, we present a high-quality genome for BN using PacBio HiFi and Hi-C sequencing technologies, with a total length of 2.66 Gb, a scaffold N50 of 143.60 Mb, and 97.59% of the sequences anchored to chromosomes. Its BUSCO score is 96.30%, higher than porcine reference assembly and DN. The genome contains 48.49% of repeats, 19,756 protein-coding genes, and 7,207 non-coding RNAs according to our annotation. The OMArk score shows a proteome completeness and consistency of 99.58% and 93.62%, respectively. These findings indicate that the chromosome-scale genome of BN provides a valuable resource for studying the genetic basis of inbreeding, facilitating further research and clinical applications.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14459
专题	科研部门_进化与生物多样性基因组学（王明山）
推荐引用方式 GB/T 7714	Chen, HM,Xu, KX,Yan, C,et al. A chromosome-scale reference genome of the Banna miniature inbred pig[J]. SCIENTIFIC DATA,2024,11(1).
APA	Chen, HM.,Xu, KX.,Yan, C.,Zhao, H.,Jiao, DL.,...&Wei, HJ.(2024).A chromosome-scale reference genome of the Banna miniature inbred pig.SCIENTIFIC DATA,11(1).
MLA	Chen, HM,et al."A chromosome-scale reference genome of the Banna miniature inbred pig".SCIENTIFIC DATA 11.1(2024).

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WMS2025040203.pdf（2499KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文