Effect of age and breeding season on the developmental capacity of oocytes from unstimulated and follicle-stimulating hormone-stimulated rhesus monkeys

	Effect of age and breeding season on the developmental capacity of oocytes from unstimulated and follicle-stimulating hormone-stimulated rhesus monkeys
	Zheng P 4,5; Si W 4,5; Wang H 4,5; Zou R 4,5; Bavister BD 3,5,6; Ji W*2,4,5; wji@mail.kiz.ac.cn
	2001
发表期刊	BIOLOGY OF REPRODUCTION
ISSN	0006-3363
卷号	64 期号:5 页码:1417-1421
合作性质	其它
摘要	Effects of age and season on the developmental capacity of oocytes from unstimulated and FSH-stimulated rhesus monkeys were examined. Immature cumulus-oocyte complexes were matured in vitro in modified CMRL-1066 medium containing 20% bovine calf serum and subjected to in vitro fertilization followed by embryo culture. After fertilization, ova from unstimulated prepubertal monkeys displayed lower development to morula (4%) than those from unstimulated adult females (18% in breeding season and 22% in nonbreeding season). No developmental difference was found between ova from unstimulated adult monkeys in breeding and nonbreeding seasons. However, ova from FSH-primed prepubertal monkeys displayed greater development to blastocyst stage (54%) than those from adult monkeys in the breeding season (16%) and nonbreeding season (0%); and ova from FSH-primed adult females in the breeding season had significantly (P < 0.05) greater developmental competence than those obtained in the nonbreeding season (> or = morula stage, 54% vs. 3%; blastocyst stage, 16% vs. 0%). These data indicate that 1) rhesus monkey oocytes acquire developmental competence in a donor age-dependent manner, and 2) animal age and breeding season modulate the effect of FSH on oocyte developmental competence in the rhesus monkey.
关键词	Aging Developmental Biology Follicular Development Fsh
资助者	Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840). ; Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840). ; Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840). ; Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840).
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收录类别	SCI
语种	英语
资助者	Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840). ; Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840). ; Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840). ; Supported by the Talent fund of Yunnan Province (96C0003G), China; projects under the Major State Basic Research Development Program, G2000016108; and is a Key Project of the Chinese Academy of Sciences KSCX1-05-02. Support was also provided by the National Institutes of Health (grants RR13439, HD-22023, and RO3-TW00840).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/2395
专题	科研部门_哺乳动物胚胎发育（郑萍）生殖与发育生物学
通讯作者	wji@mail.kiz.ac.cn
作者单位	1. 2.* 3.*** 4.Department of Primate Biology,Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China 5.The China-U.S. Primate Biology Laboratory,Kunming Institute of Zoology and University of Wisconsin-Madison, Madison, Wisconsin 53706 6.Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706
推荐引用方式 GB/T 7714	Zheng P,Si W,Wang H,et al. Effect of age and breeding season on the developmental capacity of oocytes from unstimulated and follicle-stimulating hormone-stimulated rhesus monkeys[J]. BIOLOGY OF REPRODUCTION,2001,64(5):1417-1421.
APA	Zheng P.,Si W.,Wang H.,Zou R.,Bavister BD.,...&wji@mail.kiz.ac.cn.(2001).Effect of age and breeding season on the developmental capacity of oocytes from unstimulated and follicle-stimulating hormone-stimulated rhesus monkeys.BIOLOGY OF REPRODUCTION,64(5),1417-1421.
MLA	Zheng P,et al."Effect of age and breeding season on the developmental capacity of oocytes from unstimulated and follicle-stimulating hormone-stimulated rhesus monkeys".BIOLOGY OF REPRODUCTION 64.5(2001):1417-1421.

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