The mastoparanogen from wasp

	The mastoparanogen from wasp
	Xu XQ 1,3; Yang HL 1,4; Yu HN 2; Li JX 1,3; Lai R*1; rlai@mail.kiz.ac.cn
	2006
发表期刊	PEPTIDES
ISSN	0196-9781
卷号	27 期号:12 页码:3053-3057
合作性质	其它
摘要	Mastoparans are a family of small peptides identified from the venom of hymenopteroid insects. Although they have been characterized as early as 1979, and so far are recognized as a leading biomolecule in potential drug therapy, their precursors, mastoparanogen, have still not been determined. In this paper, several mastoparans from the venom of the wasp Vespa magnifica (Smith) are reported. The cDNA of mastoparanogen is 236 base pairs in length, and encodes 40 amino acid residues, including a N-terminal acidic fragment and a C-terminal mature basic mastoparan, which contain multiple acidic amino acid residues and a tetradecapeptide with three lysines, INLKAIAALAKKLLG, respectively. The glycine at the tetradecapeptide end is the donator of -NH(4) for the amidation of the leucine at the C-terminal. As far as we know, this is the first report of the precursor of animal mastoparan.
关键词	Wasp Venom Vespa Magnifica Mastoparan Mastoparanogen Precursor G-protein
资助者	This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422). ; This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422). ; This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422). ; This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422).
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收录类别	SCI
语种	英语
资助者	This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422). ; This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422). ; This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422). ; This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/2481
专题	科研部门_天然药物功能蛋白质学科组（赖仞）科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	rlai@mail.kiz.ac.cn
作者单位	1.Biotoxin Units of Key Laboratories of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China 2.College of Life Sciences School of Heibei Normal University, Shijiazhuang, Hebei 050016, China 3.Graduate School of the Chinese Academy of Sciences, Beijing 100009, China 4.College of Animal Sciences and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, China
推荐引用方式 GB/T 7714	Xu XQ,Yang HL,Yu HN,et al. The mastoparanogen from wasp[J]. PEPTIDES,2006,27(12):3053-3057.
APA	Xu XQ,Yang HL,Yu HN,Li JX,Lai R*,&rlai@mail.kiz.ac.cn.(2006).The mastoparanogen from wasp.PEPTIDES,27(12),3053-3057.
MLA	Xu XQ,et al."The mastoparanogen from wasp".PEPTIDES 27.12(2006):3053-3057.

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