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Evolution of cd59 gene in mammals
Gong YY1,2; Peng MS1,2; Zhou WP1,3,4; Zhang YP*1,4
2007
发表期刊SCIENCE IN CHINA SERIES C-LIFE SCIENCES
ISSN1006-9305
卷号50期号:6页码:773-779
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摘要

The CD59-coding sequences were obtained from 5 mammals by PCR and BLAST, and combined with the available sequences in GenBank, the nucleotide substitution rates of mammalian cd59 were calculated. Results of synonymous and nonsynonymous substitution rates revealed that cd59 experienced negative selection in mammals overall. Four sites experiencing positive selection were found by using "site-specific" model in PAML software. These sites were distributed on the molecular surface, of which 2 sites located in the key functional domain. Furthermore, "branch-site-specific" model detected 1 positive site in cd59a and cd59b lineages which underwent accelerated evolution caused by positive selection after gene duplication in mouse.

关键词Cd59 Evolution Positive Selection
资助者Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China
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资助者Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China ; Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/4231
专题科研部门_分子进化与基因组多样性（张亚平）
遗传资源与进化国家重点实验室
作者单位1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
2.Graduate University of the Chinese Academy of Sciences, Beijing 100049, China;
3.Molecular and Cell Biology, University of Science and Technology of China, Hefei 230026, China;
4.Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, Kunming 650091, China
推荐引用方式
GB/T 7714		 Gong YY,Peng MS,Zhou WP,et al. Evolution of cd59 gene in mammals[J]. SCIENCE IN CHINA SERIES C-LIFE SCIENCES,2007,50(6):773-779.
APA Gong YY,Peng MS,Zhou WP,&Zhang YP*.(2007).Evolution of cd59 gene in mammals.SCIENCE IN CHINA SERIES C-LIFE SCIENCES,50(6),773-779.
MLA Gong YY,et al."Evolution of cd59 gene in mammals".SCIENCE IN CHINA SERIES C-LIFE SCIENCES 50.6(2007):773-779.
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