| Positive Darwinian selection in human population: A review | |
Wu DD1,3; Zhang YP*1,2
| |
| 2008 | |
| 发表期刊 | CHINESE SCIENCE BULLETIN
 |
| ISSN | 1001-6538 |
| 卷号 | 53期号:10页码:1457-1467 |
| 合作性质 | 其它 |
| 摘要 | This paper reviews a large number of genes under positive Darwinian selection in modern human populations, such as brain development genes, immunity genes, reproductive related genes, perception receptors. The research on the evolutionary property of these genes will provide important insight into human evolution and disease mechanisms. With the increase of population genetics and comparative genomics data, more and more evidences indicate that positive Darwinian selection plays an indispensable role in the origin and evolution of human beings. This paper will also summarize the methods to detect positive selection, analyze the interference factors faced and make suggestions for further research on positive selection. |
| 关键词 | Natural Selection Positive Selection Population Genetics Comparative Genomics |
| 资助者 | Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province ; Supported by the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/4291 |
| 专题 | 科研部门_分子进化与基因组多样性（张亚平） 遗传资源与进化国家重点实验室 科研部门_进化与发育转录组学（吴东东） |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2.Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, China 3.Graduate University of Chinese Academy of Sciences, Beijing 100049, China |
| 推荐引用方式 GB/T 7714 | Wu DD,Zhang YP*. Positive Darwinian selection in human population: A review[J]. CHINESE SCIENCE BULLETIN,2008,53(10):1457-1467. |
| APA | Wu DD,&Zhang YP*.(2008).Positive Darwinian selection in human population: A review.CHINESE SCIENCE BULLETIN,53(10),1457-1467. |
| MLA | Wu DD,et al."Positive Darwinian selection in human population: A review".CHINESE SCIENCE BULLETIN 53.10(2008):1457-1467. |
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