| Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system | |
| Shang EY2,3,4,6; Wang XY2,4; Huang JH2,4; Yoshida W7; Kuroiwa A7; Wolgemuth DJ*1,2,3,4,5; djw3@columbia.edu | |
| 2000 | |
| 发表期刊 | MOLECULAR REPRODUCTION AND DEVELOPMENT
 |
| ISSN | 1040-452X |
| 卷号 | 55期号:4页码:372-378 |
| 合作性质 | 其它 |
| 摘要 | We have cloned a mouse homologue (designated Myak) of the yeast protein kinase YAK1. The 1210 aa open reading frame contains a putative protein kinase domain, nuclear localization sequences and PEST sequences. Myak appears to be a member of a growing family of YAK1-related genes that include Drosophila and human Minibrain as well as a recently identified rat gene ANPK that encode a steroid hormone receptor interacting protein. RNA blot analysis revealed that Myak is expressed at low levels ubiquitously but at high levels in reproductive tissues, including testis, epididymis, ovary, uterus, and mammary gland, as well as in brain and kidney. In situ hybridization analysis on selected tissues revealed that Myak is particularly abundant in the hormonally modulated epithelia of the epididymis, mammary gland, and uterus, in round spermatids in the testis, and in the corpora lutea in the ovary, Myak is also highly expressed in the aqueduct of the adult brain and in the brain and spinal cord of day 12.5 embryos, Mol. Reprod. |
| 关键词 | Protein Kinase Transcription Complexes Hormone Modulation In Situ Hybridization Mouse Embryos |
| 资助者 | National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. ; National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. ; National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. ; National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. ; National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. ; National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. ; National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/5187 |
| 专题 | 生殖与发育生物学 |
| 通讯作者 | djw3@columbia.edu |
| 作者单位 | 1.Department of Genetics and Development, Columbia University College of Physicians and Surgeons, New York, New Yor 2.The Center for Reproductive Sciences, Columbia University College of Physicians and Surgeons, New York, New York 3.The Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, New York 4.Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York 5.The Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York 6.The Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan, China 7.Divison of Biological Science, Nagoya University, Japan |
| 推荐引用方式 GB/T 7714 | Shang EY,Wang XY,Huang JH,et al. Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system[J]. MOLECULAR REPRODUCTION AND DEVELOPMENT,2000,55(4):372-378. |
| APA | Shang EY.,Wang XY.,Huang JH.,Yoshida W.,Kuroiwa A.,...&djw3@columbia.edu.(2000).Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system.MOLECULAR REPRODUCTION AND DEVELOPMENT,55(4),372-378. |
| MLA | Shang EY,et al."Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system".MOLECULAR REPRODUCTION AND DEVELOPMENT 55.4(2000):372-378. |
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| 200055372.pdf（870KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
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