KMS KUNMING INSTITUTE OF ZOOLOGY.CAS
| Molecular genetic basis for the rhino mouse from Chinese KM subcolony | |
Tian M1,2,4; Xiong YL3; Wang WY3; Zhang YP*1,2
| |
| 2004 | |
| 发表期刊 | CHINESE SCIENCE BULLETIN
 |
| ISSN | 1001-6538 |
| 卷号 | 49期号:2页码:146-152 |
| 合作性质 | 其它 |
| 摘要 | Both the rhino mouse and hairless mouse resulted from hairless gene mutation, but they show different phenotypes of skin physiology. The rhino mouse has more similar histological characters to human papular alopecia. Therefore rhino mouse is a good experimental animal model for human papular alopecia. This study reports a hairless mouse named rhino KIZ, arose from KM colony in Kunming Institue of Zoology, by systematic studies on morphology, skin histopathology, gene sequence, pedigree and protein domain analysis. The results demonstrate that a C-to-T transition in exon 11 of hr gene (The mutant gene has been applied for a Chinese patent (patent No. 03135280)) results in the rhino KIZ. The rhino KIZ with clear genetic mechanism will be a useful animal model. |
| 关键词 | Km Mouse Shedding Hair Mutation Rhino Mouse Hairless (Hr) Gene |
| 资助者 | This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). ; This work was supported by the National Natural Science Foundation of China (Grant No. 30024004). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/5323 |
| 专题 | 其他 科研部门_分子进化与基因组多样性（张亚平） 细胞与分子进化重点实验室 |
| 作者单位 | 1.Yunnan Key Laboratory of Molecular Biology of Domestic Animals, Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2.Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, China 3.Department of Animal Toxinology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 4.Graduate School of the Chinese Academy of Sciences, Beijing 100039, China |
| 推荐引用方式 GB/T 7714 | Tian M,Xiong YL,Wang WY,et al. Molecular genetic basis for the rhino mouse from Chinese KM subcolony[J]. CHINESE SCIENCE BULLETIN,2004,49(2):146-152. |
| APA | Tian M,Xiong YL,Wang WY,&Zhang YP*.(2004).Molecular genetic basis for the rhino mouse from Chinese KM subcolony.CHINESE SCIENCE BULLETIN,49(2),146-152. |
| MLA | Tian M,et al."Molecular genetic basis for the rhino mouse from Chinese KM subcolony".CHINESE SCIENCE BULLETIN 49.2(2004):146-152. |
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