Abnormal regional homogeneity of drug-naive obsessive-compulsive patients
Yang T1; Cheng YQ1,2,4; Li HJ3; Jiang HY1; Luo CR3; Shan BC5; Xu L2,4; Xu XF*1; xfxu2004@sina.com
2010
发表期刊NEUROREPORT
ISSN0959-4965
卷号21期号:11页码:786-790
合作性质其它
摘要To explore the possible abnormal resting-state activity in patients with obsessive-compulsive disorder (OCD), the regional homogeneity (ReHo) of 22 pairs of patients and well-matched healthy controls was calculated. Compared with controls, the patients showed higher ReHo in the left anterior cingulate cortex, but lower ReHo in the left inferior temporal gyrus. These findings supported the abnormal resting-state brain activity in drug-naive OCD patients. No significant correlations between ReHo value and four clinical characteristics were found, suggesting that abnormal ReHo might be trait-related in OCD.
关键词Functional Magnetic Resonance Imaging Obsessive-compulsive Disorder Regional Homogeneity Resting-state
学科领域Neurosciences
资助者This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092).
收录类别SCI
语种英语
资助者This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092).
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/5937
专题科研部门_学习记忆的分子神经机制(徐林)
科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者xfxu2004@sina.com
作者单位1.Department of Psychiatry, The First Affiliated Hospital of Kunming Medical College
2.Key Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences, Kunming Institute of Zoology
3.Magnetic Resonance Imaging Center,The First Hospital of Kunming City, Kunming,Yunnan
4.Graduate School of Chinese Academy of Sciences
5.Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China
推荐引用方式
GB/T 7714
Yang T,Cheng YQ,Li HJ,et al. Abnormal regional homogeneity of drug-naive obsessive-compulsive patients[J]. NEUROREPORT,2010,21(11):786-790.
APA Yang T.,Cheng YQ.,Li HJ.,Jiang HY.,Luo CR.,...&xfxu2004@sina.com.(2010).Abnormal regional homogeneity of drug-naive obsessive-compulsive patients.NEUROREPORT,21(11),786-790.
MLA Yang T,et al."Abnormal regional homogeneity of drug-naive obsessive-compulsive patients".NEUROREPORT 21.11(2010):786-790.
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