| Abnormal regional homogeneity of drug-naive obsessive-compulsive patients | |
| Yang T1; Cheng YQ1,2,4; Li HJ3; Jiang HY1; Luo CR3; Shan BC5; Xu L2,4; Xu XF*1; xfxu2004@sina.com | |
| 2010 | |
| 发表期刊 | NEUROREPORT
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| ISSN | 0959-4965 |
| 卷号 | 21期号:11页码:786-790 |
| 合作性质 | 其它 |
| 摘要 | To explore the possible abnormal resting-state activity in patients with obsessive-compulsive disorder (OCD), the regional homogeneity (ReHo) of 22 pairs of patients and well-matched healthy controls was calculated. Compared with controls, the patients showed higher ReHo in the left anterior cingulate cortex, but lower ReHo in the left inferior temporal gyrus. These findings supported the abnormal resting-state brain activity in drug-naive OCD patients. No significant correlations between ReHo value and four clinical characteristics were found, suggesting that abnormal ReHo might be trait-related in OCD. |
| 关键词 | Functional Magnetic Resonance Imaging Obsessive-compulsive Disorder Regional Homogeneity Resting-state |
| 学科领域 | Neurosciences |
| 资助者 | This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). ; This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/5937 |
| 专题 | 科研部门_学习记忆的分子神经机制(徐林) 科研部门_动物模型与人类重大疾病机理重点实验室 |
| 通讯作者 | xfxu2004@sina.com |
| 作者单位 | 1.Department of Psychiatry, The First Affiliated Hospital of Kunming Medical College 2.Key Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences, Kunming Institute of Zoology 3.Magnetic Resonance Imaging Center,The First Hospital of Kunming City, Kunming,Yunnan 4.Graduate School of Chinese Academy of Sciences 5.Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China |
| 推荐引用方式 GB/T 7714 | Yang T,Cheng YQ,Li HJ,et al. Abnormal regional homogeneity of drug-naive obsessive-compulsive patients[J]. NEUROREPORT,2010,21(11):786-790. |
| APA | Yang T.,Cheng YQ.,Li HJ.,Jiang HY.,Luo CR.,...&xfxu2004@sina.com.(2010).Abnormal regional homogeneity of drug-naive obsessive-compulsive patients.NEUROREPORT,21(11),786-790. |
| MLA | Yang T,et al."Abnormal regional homogeneity of drug-naive obsessive-compulsive patients".NEUROREPORT 21.11(2010):786-790. |
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