Phylogeny of mitochondrial DNA macrohaplogroup N in India, based on complete sequencing: Implications for the peopling of South Asia

	Phylogeny of mitochondrial DNA macrohaplogroup N in India, based on complete sequencing: Implications for the peopling of South Asia
	Palanichamy MG 1,2; Sun C 2,3; Agrawal S 4; Bandelt HJ 5; Kong QP 2,3; Khan F 4; Wang CY 2,3; Chaudhuri TK 6; Palla V 7; Zhang YP*1,2
	2004
发表期刊	AMERICAN JOURNAL OF HUMAN GENETICS
ISSN	0002-9297
卷号	75 期号:6 页码:966-978
合作性质	其它
摘要	To resolve the phylogeny of the autochthonous mitochondrial DNA (mtDNA) haplogroups of India and determine the relationship between the Indian and western Eurasian mtDNA pools more precisely, a diverse subset of 75 macrohaplogroup N lineages was chosen for complete sequencing from a collection of >1800 control-region sequences sampled across India. We identified five new autochthonous haplogroups (R7, R8, R30, R31, and N5) and fully characterized the autochthonous haplogroups (R5, R6, N1d, U2a, U2b, and U2c) that were previously described only by first hypervariable segment (HVS-I) sequencing and coding-region restriction-fragment-length polymorphism analysis. Our findings demonstrate that the Indian mtDNA pool, even when restricted to macrohaplogroup N, harbors at least as many deepest-branching lineages as the western Eurasian mtDNA pool. Moreover, the distribution of the earliest branches within haplogroups M, N, and R across Eurasia and Oceania provides additional evidence for a three-founder-mtDNA scenario and a single migration route out of Africa.
资助者	The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010.
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资助者	The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010. ; The work was supported by National Natural Science Foundation of China grant 30021004, National Key Technologies R&D Program of China and Science and Technology Committee of Yunnan Province grant 2004BA901A07, and Chinese Academy of Sciences grant KSCX2-SW-2010.
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/6039
专题	科研部门_分子进化与基因组多样性（张亚平）科研部门_分子人类学（孔庆鹏）细胞与分子进化开放实验室
作者单位	1.Laboratory for Conservation and Utilization of Bioresources, Yunnan University 2.Laboratory of Cellular and Molecular Evolution and Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 3.Graduate School of the Chinese Academy of Sciences, Beijing 4.Department of Medical Genetics, Sanjay Gandhi Institute of Medical Sciences, Lucknow, India 5.Fachbereich Mathematik, Universita ¨t Hamburg, Hambur 6.Department of Zoology, North Bengal University, Siliguri West Bengal, India 7.Department of Anthropology, Sri Venkateswara University, Tirupati, India
推荐引用方式 GB/T 7714	Palanichamy MG,Sun C,Agrawal S,et al. Phylogeny of mitochondrial DNA macrohaplogroup N in India, based on complete sequencing: Implications for the peopling of South Asia[J]. AMERICAN JOURNAL OF HUMAN GENETICS,2004,75(6):966-978.
APA	Palanichamy MG.,Sun C.,Agrawal S.,Bandelt HJ.,Kong QP.,...&Zhang YP*.(2004).Phylogeny of mitochondrial DNA macrohaplogroup N in India, based on complete sequencing: Implications for the peopling of South Asia.AMERICAN JOURNAL OF HUMAN GENETICS,75(6),966-978.
MLA	Palanichamy MG,et al."Phylogeny of mitochondrial DNA macrohaplogroup N in India, based on complete sequencing: Implications for the peopling of South Asia".AMERICAN JOURNAL OF HUMAN GENETICS 75.6(2004):966-978.

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