HCCS1 overexpression induces apoptosis via cathepsin D and intracellular calcium, and HCCS1 disruption in mice causes placental abnormality

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	HCCS1 overexpression induces apoptosis via cathepsin D and intracellular calcium, and HCCS1 disruption in mice causes placental abnormality
	Gan Y 1; Zhao X2 ; Hu J 1; Wang ZG2; Zhao XD1; xtzhao@online.sh.cn ; zhugangw@shsmu.edu.cn
	2008
发表期刊	Cell Death and Differentiation
卷号	15 期号:9 页码:1481-1490
摘要	Hepatocellular carcinoma suppressor 1 (HCCS1) was discovered as a novel tumor suppressor gene. We recently observed that adenovirus-mediated gene transfer of HCCS1 leads to cytotoxicity to human hepatocarcinoma cells. Here, we have demonstrated that adenovirus-mediated overexpression of HCCS1 induces apoptosis in hepatocarcinoma cells and have further characterized the apoptotic cascade. The results showed that lysosomal cathepsin D is released into the cytosol in response to HCCS1 overexpression and consequently triggers Bax insertion into the mitochondrial membrane, which leads to the release of cytochrome c. In addition, HCCS1 overexpression can induce an increase in intracellular free Ca(2+) concentration, which also results in cytochrome c release. The released cytochrome c activates downstream caspases, leading to the occurrence of the late stages of apoptosis. Moreover, we demonstrated that the disruption of HCCS1 in mice leads to embryonic lethality, accompanied by abnormal labyrinth architecture resulting from the excessive proliferation of trophoblast cells in the placenta. These results suggest that HCCS1 plays a role in apoptosis regulation and development.
关键词	Hepatocellular Carcinoma Suppressor 1 Calcium Cathepsin d Labyrinth Abnormality
资助者	This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015).
收录类别	SCI
语种	英语
资助者	This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015). ; This work was supported by grants from the Key Programs of the National Natural Science Foundation of China (No. 30330350) and the Shanghai Committee of Science and Technology (No. 04XD14015).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/7941
专题	科研共享资源
通讯作者	xtzhao@online.sh.cn; zhugangw@shsmu.edu.cn
作者单位	1.Laboratory for Cellular and Molecular Immunology, Shanghai Cancer Institute, Shanghai 200032, P.R. China 2.Shanghai Research Center for Model Organisms, Shanghai 201210, P.R. China
推荐引用方式 GB/T 7714	Gan Y,Zhao X,Hu J,et al. HCCS1 overexpression induces apoptosis via cathepsin D and intracellular calcium, and HCCS1 disruption in mice causes placental abnormality[J]. Cell Death and Differentiation,2008,15(9):1481-1490.
APA	Gan Y.,Zhao X.,Hu J.,Wang ZG.,Zhao XD.,...&zhugangw@shsmu.edu.cn.(2008).HCCS1 overexpression induces apoptosis via cathepsin D and intracellular calcium, and HCCS1 disruption in mice causes placental abnormality.Cell Death and Differentiation,15(9),1481-1490.
MLA	Gan Y,et al."HCCS1 overexpression induces apoptosis via cathepsin D and intracellular calcium, and HCCS1 disruption in mice causes placental abnormality".Cell Death and Differentiation 15.9(2008):1481-1490.

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