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	Hippo pathway in mammary gland development and breast cancer
	Shi PG1,2; Feng J*3; Chen CS*1; fengjing8801530@163.com; chenc@mail.kiz.ac.cn
	2015
发表期刊	ACTA BIOCHIMICA ET BIOPHYSICA SINICA
卷号	47期号:1页码:53-59
合作性质	其它
摘要	Accumulated evidence suggests that the Hippo signaling pathway plays crucial roles in mammary gland development and breast cancer. Key components of the Hippo pathway regulate breast epithelial cell proliferation, migration, invasion, and stemness. Additionally, the Hippo pathway regulates breast tumor growth, metastasis, and drug resistance. It is expected that the Hippo pathway will provide novel therapeutic targets for breast cancer. This review will discuss and summarize the roles of several core components of the Hippo pathway in mammary gland development and breast cancer.
关键词	Hippo Pathway Yap Taz Mammary Gland Development Breast Cancer
资助者	This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605).
收录类别	SCI
语种	英语
资助者	This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605). ; This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/8248
专题	科研部门_肿瘤生物学（陈策实） 科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	fengjing8801530@163.com; chenc@mail.kiz.ac.cn
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Chinese Academy of Sciences, Kunming Institute of Zoology, Kunming 650223, China 2.University of Chinese Academy of Sciences, Beijing 100049, China 3.Department of laboratory medicine & Central Laboratory, South Medical University Affiliated Fengxian Hospital, Shanghai 201499, China
推荐引用方式 GB/T 7714	Shi PG,Feng J*,Chen CS*,et al. Hippo pathway in mammary gland development and breast cancer[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2015,47(1):53-59.
APA	Shi PG,Feng J*,Chen CS*,fengjing8801530@163.com,&chenc@mail.kiz.ac.cn.(2015).Hippo pathway in mammary gland development and breast cancer.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,47(1),53-59.
MLA	Shi PG,et al."Hippo pathway in mammary gland development and breast cancer".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 47.1(2015):53-59.

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