分子人类学（孔庆鹏）知识库

本文以人类线粒体DNA为例,回顾了其系统发育关系的重建的研究历史,进而总结介绍了该分析方法在人类进化历史研究、线粒体DNA数据质量评估以及疾病相关线粒体DNA突变的甄别等方面的应用,以期对该方法在国内的推广应用有所裨益。

With the special intention to introduce the most widely adopted phylogenetic analysis human mitochondrial DNA （mtDNA）studies, the history of the reconstruction of mtDNA phylogeny was reviewed. And the applications of human mtDNA phylogeny in studying human evolution, estimating the quality of mtDNA data, and distilling the disease-associated mtDNA mutation were then summarized in the present review.