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	Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus)
	Liu Y1; Ye J*1,2; Su W1; Yang F3; Nie W1; Fu B3; Ng BL3; Wang J1; yjpyyjjpp@hotmail.com
	2011
发表期刊	CYTOGENETIC AND GENOME RESEARCH
卷号	132期号:1-2页码:31-40
合作性质	其它
摘要	Xenarthra, as the probable earliest offshoot of the placental tree, represents a key taxon for understanding mammalian phylogeny. To gain further insight into the chromosomal evolution and genome organization of the xenarthrans, we have established the first genome-wide comparative chromosome map between human and the 6-banded armadillo (Euphractus sexcinctus, 2n = 58), a basal species on the Xenarthra branch, by reciprocal cross-species chromosome painting. In total, 22 human autosomal paints revealed 41 homologous segments in the euchromatic genome of E. sexcinctus. Our results provide further support for the notion that the 2 human homologous segmental associations, i.e. HSA 2/8 and 7a/10p, could constitute the synapomorphies that unite the xenarthrans. Moreover, we propose that the putative ancestral Xenarthra karyotype closely resemble the 2n = 54 karyotype of the E. sexcinctus, consisting of the equivalents of HSA1p, 1q, 2a, 2b, 2c/8c, 3/21, 4a, 4b/8b, 5, 6a, 6b, 7a/10p, 7b/16p, 8a, 9, 10q, 11, 12a/22a, 12b/22b, 13, 14/15, 16q/19q, 17, 18, 19p, 20, and X. In addition, we have analysed the C-banding patterns of E. sexcinctus, and cloned, FISH-mapped and sequenced 7 novel repetitive DNA segments, providing further information on the complexity of genome architecture of E. sexcinctus.
关键词	6-banded Armadillo Ancestral Xenarthra Karyotype Cloning Cross-species Chromosome Painting Fish Mapping Repetitive Dnas Sequencing
资助者	This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008).
收录类别	SCI
语种	英语
资助者	This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). ; This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/9612
专题	遗传资源与进化国家重点实验室_保护遗传学(细胞库) 遗传资源与进化国家重点实验室
通讯作者	yjpyyjjpp@hotmail.com
作者单位	1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, China 2.College of Life Sciences, Shaoxing University, Shaoxing , PR China 3.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton , UK
推荐引用方式 GB/T 7714	Liu Y,Ye J*,Su W,et al. Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus)[J]. CYTOGENETIC AND GENOME RESEARCH,2011,132(1-2):31-40.
APA	Liu Y.,Ye J*.,Su W.,Yang F.,Nie W.,...&yjpyyjjpp@hotmail.com.(2011).Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus).CYTOGENETIC AND GENOME RESEARCH,132(1-2),31-40.
MLA	Liu Y,et al."Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus)".CYTOGENETIC AND GENOME RESEARCH 132.1-2(2011):31-40.

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