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A folding "framework structure" of Tetrahymena group I intron
Zhang X1,2; Guo C1; Zhang W1,3; Cao HA1; Xie HZ1; Wang K1; Liu CQ*1,4,5; liucq@ynu.edu.cn
2010
发表期刊JOURNAL OF THEORETICAL BIOLOGY
卷号267期号:4页码:495-501
合作性质其它
摘要We have published the dynamic extended folding (DEF) method which is a RNA secondary structure prediction approach to simulate the in vivo RNA co-transcriptional folding process In order to verify the reliability of the method we selected the X-ray-determined Tetrahymena group I intron as a sample to construct the framework of its folding secondary structure Our prediction coincides well with the secondary structure predicted by T R. Cech and the X-ray diffraction crystal structure determined by Lehnert V Our results show that the DEF framework structure of Tetrahymena group I intron reflects its function sites in a concise and straightforward manner and the scope of the simulation was expanded
关键词Ribozyme Dynamic Extended Folding Splice Site Rna Secondary Structure
资助者This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454). ; This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454). ; This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454). ; This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454).
收录类别SCI
语种英语
资助者This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454). ; This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454). ; This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454). ; This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454).
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/353002/6545
专题其他
通讯作者liucq@ynu.edu.cn
作者单位1.Modern Biological Research Center, Yunnan University, Kunming 650091, China
2.Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310029, China
3.Department of Cell Biology and Genetics, Kunming Medical College, Kunming 650031, China
4.Kunming Institute of Zoology, Chinese Academy of Science, Kunming 650223, China
5.Center of Theoretical Biology, Peking University, Beijing 100871, China
推荐引用方式
GB/T 7714
Zhang X,Guo C,Zhang W,et al. A folding "framework structure" of Tetrahymena group I intron[J]. JOURNAL OF THEORETICAL BIOLOGY,2010,267(4):495-501.
APA Zhang X.,Guo C.,Zhang W.,Cao HA.,Xie HZ.,...&liucq@ynu.edu.cn.(2010).A folding "framework structure" of Tetrahymena group I intron.JOURNAL OF THEORETICAL BIOLOGY,267(4),495-501.
MLA Zhang X,et al."A folding "framework structure" of Tetrahymena group I intron".JOURNAL OF THEORETICAL BIOLOGY 267.4(2010):495-501.
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