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KLF5 inhibition potentiates anti-PD1 efficacy by enhancing CD8+T-cell-dependent antitumor immunity 期刊论文
THERANOSTICS, 2023, 卷号: 13, 期号: 4, 页码: 1381-1400
作者:  Wu, Q;  Liu, Z;  Gao, ZJ;  Luo, Y;  Li, FB;  Yang, CY;  Wang, TT;  Meng, XY;  Chen, HJ;  Li, JJ;  Kong, YJ;  Dong, C;  Sun, S;  Chen, CS
Adobe PDF(10340Kb)  |  收藏  |  浏览/下载：107/0  |  提交时间：2024/06/21
The landscape of aging 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2022, 卷号: 65, 期号: 12, 页码: 2354-2454
作者:  Cai, YS;  Song, W;  Li, JM;  Jing, Y;  Liang, CQ;  Zhang, LY;  Zhang, X;  Zhang, WH;  Liu, BB;  An, YP;  Li, JY;  Tang, BX;  Pei, SY;  Wu, XY;  Liu, YX;  Zhuang, CL;  Ying, YL;  Dou, XF;  Chen, Y;  Xiao, FH;  Li, DF;  Yang, RC;  Zhao, Y;  Wang, Y;  Wang, LH;  Li, YJ;  Ma, S;  Wang, S;  Song, XY;  Ren, J;  Zhang, L;  Wang, J;  Zhang, WQ;  Xie, ZW;  Qu, J;  Wang, JW;  Xiao, YCA;  Tian, Y;  Wang, GL;  Hu, P;  Ye, J;  Sun, Y;  Mao, ZY;  Kong, QP;  Liu, Q;  Zou, WG;  Tian, XL;  Xiao, ZX;  Liu, Y;  Liu, JP;  Song, MS;  Han, JDJ;  Liu, GH
Adobe PDF(7082Kb)  |  收藏  |  浏览/下载：1592/0  |  提交时间：2023/04/18
Histone Deacetylase Inhibitors (HDACi) Promote KLF5 Ubiquitination and Degradation in Basal-like Breast Cancer 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 卷号: 18, 期号: 5, 页码: 2104-2115
作者:  Kong, YJ;  Ren, WL;  Fang, H;  Shah, NA;  Shi, YJ;  You, DY;  Zhou, CG;  Jiang, DW;  Yang, CAY;  Liang, HC;  Liu, WJ;  Wang, LZ;  Gan, WQ;  Wan, X;  Li, FB;  Li, Z;  Chen, CS;  Xie, N
Adobe PDF(2239Kb)  |  收藏  |  浏览/下载：1204/0  |  提交时间：2023/04/18
Targeting HECTD3-IKK alpha axis inhibits inflammation-related metastasis 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 卷号: 7, 期号: 1
作者:  Li, FB;  Liang, HC;  You, H;  Xiao, J;  Xia, HJ;  Chen, X;  Huang, MB;  Cheng, Z;  Yang, CY;  Liu, WJ;  Zhang, HL;  Zeng, L;  Wu, YY;  Ge, F;  Li, Z;  Zhou, WH;  Wen, Y;  Zhou, ZM;  Liu, R;  Jiang, DW;  Xie, N;  Bin L;  Liu, ZZ;  Kong, YJ;  Chen, CS
Adobe PDF(6633Kb)  |  收藏  |  浏览/下载：1244/0  |  提交时间：2023/04/18
Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib 期刊论文
CANCER LETTERS, 2021, 卷号: 504, 页码: 125-136
作者:  Huang, MB;  Zhou, YF;  Duan, DZ;  Yang, CY;  Zhou, ZM;  Li, FB;  Kong, YJ;  Hsieh, YC;  Zhang, RH;  Ding, WP;  Xiao, WL;  Puno, P;  Chen, CS
Adobe PDF(9762Kb)  |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/18
Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan 期刊论文
NATURE GENETICS, 2021, 卷号: 53, 期号: 5, 页码: 742-+
作者:  Lu, ZM;  Gong, L;  Ren, YD;  Chen, YJ;  Wang, ZK;  Liu, LQ;  Li, HR;  Chen, XQ;  Li, ZZ;  Luo, HR;  Jiang, H;  Zeng, Y;  Wang, YF;  Wang, K;  Zhang, C;  Jiang, HF;  Wan, WT;  Qin, YL;  Zhang, JS;  Zhu, L;  Shi, W;  He, SP;  Mao, BY;  Wang, W;  Kong, XY;  Li, YX
Adobe PDF(30960Kb)  |  收藏  |  浏览/下载：1645/0  |  提交时间：2023/04/12
The role of E3 ubiquitin ligase HECTD3 in cancer and beyond 期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2020, 卷号: 77, 期号: 8, 页码: 1483-1495
作者:  Jiang, QY;  Li, FB;  Cheng, Z;  Kong, YJ;  Chen, CS
Adobe PDF(2392Kb)  |  收藏  |  浏览/下载：175/0  |  提交时间：2021/11/18
CUL7 promotes cancer cell survival through promoting Caspase-8 ubiquitination 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 5, 页码: 1371-1381
作者:  Kong, YJ;  Wang, ZH;  Huang, MB;  Zhou, ZM;  Li, Y;  Miao, HL;  Wan, X;  Huang, J;  Mao, XY;  Chen, CS
Adobe PDF(1992Kb)  |  收藏  |  浏览/下载：151/0  |  提交时间：2021/11/18
Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation 期刊论文
Cell Discovery, 2017, 卷号: 3, 期号: X, 页码: e17010
作者:  Shi PG;  Liu WJ;  Zhang HL;  Wu YY;  Kong YJ;  Zhou ZM;  Wang CY;  Chen WL;  Tala;  Liu R;  Chen CS*;  Wang HX;  Li FB;  chenc@mail.kiz.ac.cn
Adobe PDF(2954Kb)  |  收藏  |  浏览/下载：114/2  |  提交时间：2017/04/21
Klf5  Metformin  Pka  Stem Cells  Triple-negative Breast Cancer  
诱导乳腺癌细胞凋亡的天然产物筛选和抗凋亡泛素连接酶HECTD3 作用机制研究 学位论文
, 北京: 中国科学院研究生院, 2016
作者:  孔燕杰
Adobe PDF(5755Kb)  |  收藏  |  浏览/下载：124/1  |  提交时间：2017/07/27
三阴性乳腺癌  Khf16  葫芦素e  Hectd3  泛素化  细胞凋亡