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脑容量调控基因 MCPH1人源化小鼠模型的构建与初步研究 学位论文
理学硕士, 北京: 中国科学院大学, 2018
作者:  黄俊
Adobe PDF(4360Kb)  |  收藏  |  浏览/下载:171/2  |  提交时间:2019/08/30
大脑进化,大脑发育,mcph1,人类特异突变,crispr/cas9 基因编  Brain Evolution, Brain Development, Mcph1, Human-specific Mutations, Crispr/cas9 Gene Editing Technique, Mouse Model  
Comparative Methylome Analyses Identify Epigenetic Regulatory Loci of Human Brain Evolution 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2016, 卷号: 33, 期号: 11, 页码: 2947-2959
作者:  Mendizabal I;  Shi L;  Keller TE;  Konopka G;  Preuss TM;  Hsieh TF;  Hu EZ;  Zhang Z;  Su B*;  Yi SV*
Adobe PDF(890Kb)  |  收藏  |  浏览/下载:113/3  |  提交时间:2016/08/26
Dna Methylation  Human Brain Evolution  Transcriptional Divergence  Differentially Methylated Regions  Epigenomes  
Integrative analyses of RNA editing, alternative splicing, and expression of young genes in human brain transcriptome by deep RNA sequencing 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2015, 卷号: 7, 期号: 4, 页码: 314-325
作者:  Wu DD;  Ye LQ;  Li Y;  Sun YB;  Shao Y;  Chen CY;  Zhu Z;  Zhong L;  Wang L;  Irwin DM;  Zhang YE;  Zhang YP*
Adobe PDF(1219Kb)  |  收藏  |  浏览/下载:1462/4  |  提交时间:2015/09/08
Rna Editing  Human Brain Transcriptome  Young Gene  Human Brain Evolution  
Genetic Adaptation of the Hypoxia-Inducible Factor Pathway to Oxygen Pressure among Eurasian Human Populations 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2012, 卷号: 29, 期号: 11, 页码: 3359-3370
作者:  Ji LD;  Qiu YQ;  Xu J;  Irwin DM;  Tam SC;  Tang NLS*;  Zhang YP*
Adobe PDF(613Kb)  |  收藏  |  浏览/下载:189/5  |  提交时间:2013/04/09
Adaptive Evolution  Human Genetic Variation  Oxygen Pressure  Hypoxia  Hypoxia-inducible Factor Pathway  Eurasian Populations  
Functional characterization of the human-specific (type II) form of kallikrein 8, a gene involved in learning and memory 期刊论文
CELL RESEARCH, 2009, 卷号: 19, 期号: 2, 页码: 259-267
作者:  Lu ZX;  Huang Q;  Su B*
Adobe PDF(793Kb)  |  收藏  |  浏览/下载:170/4  |  提交时间:2010/08/24
Type Ii Klk8  Alternative Splicing  Cognition  Human Evolution  
The role of climate in human mitochondrial DNA evolution: A reappraisal 期刊论文
GENOMICS, 2007, 卷号: 89, 期号: 3, 页码: 338-342
作者:  Sun C;  Kong QP;  Zhang YP*
Adobe PDF(131Kb)  |  收藏  |  浏览/下载:135/5  |  提交时间:2010/08/24
Human Mitochondrial Dna  Evolution  Selection  Climate  
Rapid evolution, genetic variations, and functional association of the human spermatogenesis-related gene NYD-SP12 期刊论文
JOURNAL OF MOLECULAR EVOLUTION, 2007, 卷号: 65, 期号: 2, 页码: 154-161
作者:  Zhang Q;  Zhang F;  Chen XH;  Wang YQ;  Wang WQ;  Alice AL;  Jin L;  Huo R;  Sha JH;  Li Z;  Su B*
Adobe PDF(296Kb)  |  收藏  |  浏览/下载:160/2  |  提交时间:2010/08/24
Genetic Variations  Darwinian Posi- Tive Selectio  Spermatogenesis  Sexual Selection  Human Evolution  
Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2007, 卷号: 24, 期号: 9, 页码: 1991-2000
作者:  Jiang CZ;  Han L;  Su B;  Li WH;  Zhao ZM*
Adobe PDF(293Kb)  |  收藏  |  浏览/下载:217/2  |  提交时间:2016/10/09
Cpg Island Evolution  Promoter  Dna Methylation  Functional Bias  Human  Mouse  
A human-specific mutation leads to the origin of a novel splice form of neuropsin (KLK8), a gene involved in learning and memory 期刊论文
HUMAN MUTATION, 2007, 卷号: 28, 期号: 10, 页码: 978-984
作者:  Lu ZX;  Peng J;  Su B*
Adobe PDF(391Kb)  |  收藏  |  浏览/下载:249/2  |  提交时间:2010/08/24
Neuropsin  Kallikrein 8  Klk8  Alternative Splicing  Cognition  Human Evolution  
The testis-specific apoptosis related gene TTL.6 underwent adaptive evolution in the lineage leading to humans 期刊论文
GENE, 2006, 卷号: 370, 期号: X, 页码: 58-63
作者:  Chen XH;  Shi H;  Liu XL;  Su B*
Adobe PDF(129Kb)  |  收藏  |  浏览/下载:150/4  |  提交时间:2010/08/24
Positive Selection  Sexual Selection  Human Evolution  Male Reproductive Genes  Tubulin-tyrosine Ligase