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Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan, Y;  Ran, XQ;  Wang, D;  Zhang, X;  Peng, MY;  Yan, XY;  Tang, L;  Liang, H;  Qin, XJ;  Di, YT;  Luo, RC;  Hao, XJ;  Yao, YG
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载:3690/0  |  提交时间:2023/04/12
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 132
作者:  Peng, XR;  Luo, RC;  Ran, XQ;  Guo, YR;  Yao, YG;  Qiu, MH
Adobe PDF(3003Kb)  |  收藏  |  浏览/下载:1651/0  |  提交时间:2024/06/21
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit β-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2
作者:  Li, S;  Han, LL;  Huang, KP;  Ma, YH;  Guo, LL;  Guo, YR;  Ran, XQ;  Yao, YG;  Hao, XJ;  Luo, RC;  Zhang, Y
Adobe PDF(5266Kb)  |  收藏  |  浏览/下载:1603/0  |  提交时间:2024/06/21
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2
作者:  Ran, XQ;  Lu, QY;  Li, YY;  Pu, XX;  Guo, YR;  Yuan, MR;  Guan, SP;  Sun, M;  Jiao, LJ;  Yao, YG;  Di, YT;  Hao, XJ;  Luo, RC
Adobe PDF(10283Kb)  |  收藏  |  浏览/下载:91/0  |  提交时间:2024/06/21
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2
作者:  Yan, Y;  Zhou, Q;  Ran, XQ;  Lu, QY;  Zhang, CS;  Peng, MY;  Tang, L;  Luo, RC;  Di, YT;  Hao, XJ
Adobe PDF(11343Kb)  |  收藏  |  浏览/下载:715/0  |  提交时间:2024/06/21
Monoterpenoid indole alkaloid dimers from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation 期刊论文
PHYTOCHEMISTRY, 2022, 卷号: 203
作者:  Chen, C;  Liu, JW;  Guo, LL;  Xiong, F;  Ran, XQ;  Guo, YR;  Yao, YG;  Hao, XJ;  Luo, RC;  Zhang, Y
Adobe PDF(7177Kb)  |  收藏  |  浏览/下载:1790/0  |  提交时间:2023/04/12
(+/-)-Spiroganoapplanin A, a complex polycyclic meroterpenoid dimer from Ganoderma applanatum displaying potential against Alzheimer's disease 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2022, 卷号: 9, 期号: 11, 页码: 3093-3101
作者:  Peng, XR;  Luo, RC;  Su, HG;  Zhou, L;  Ran, XQ;  Guo, YR;  Yao, YG;  Qiu, MH
Adobe PDF(3166Kb)  |  收藏  |  浏览/下载:1790/0  |  提交时间:2023/04/12
A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-beta pathology and cognitive decline 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1
作者:  Luo, RC;  Fan, Y;  Yang, J;  Ye, MS;  Zhang, DF;  Guo, K;  Li, X;  Bi, R;  Xu, M;  Yang, LX;  Li, Y;  Ran, XQ;  Jiang, HY;  Zhang, C;  Tan, LW;  Sheng, NY;  Yao, YG
Adobe PDF(7348Kb)  |  收藏  |  浏览/下载:1695/0  |  提交时间:2023/04/12
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang, XH;  Luo, RC;  Ye, MS;  Tang, HY;  Ma, YL;  Chen, YN;  Wang, XM;  Lu, QY;  Liu, S;  Li, XN;  Yan, Y;  Yang, J;  Ran, XQ;  Fang, X;  Zhou, Y;  Yao, YG;  Di, YT;  Hao, XJ
Adobe PDF(2401Kb)  |  收藏  |  浏览/下载:1512/0  |  提交时间:2023/04/12
Perforatactones D and E, two new C-20 quassinoids with potential activity to induce lysosomal biogenesis from the twigs of Harrisonia perforata (Blanco) Merr. 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 44, 页码: 9637-9640
作者:  Liu, S;  Zhang, CS;  Ran, XQ;  Tang, XH;  Guo, YR;  Yan, Y;  Yao, YG;  Hao, XJ;  Luo, RC;  Di, YT
Adobe PDF(1866Kb)  |  收藏  |  浏览/下载:34/0  |  提交时间:2023/04/12