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A framework for detecting causal effects of risk factors at an individual level based on principles of Mendelian randomisation: applications to modelling individualised effects of lipids on coronary artery disease 期刊论文
EBIOMEDICINE, 2025, 卷号: 113
作者:  Shi, YJ;  Xiang, Y;  Ye, YX;  He, TW;  Sham, PC;  So, HC
Adobe PDF(2005Kb)  |  收藏  |  浏览/下载：199/0  |  提交时间：2025/04/21
Unraveling NEK4 as a Potential Drug Target in Schizophrenia and Bipolar I Disorder: A Proteomic and Genomic Approach 期刊论文
SCHIZOPHRENIA BULLETIN, 2024
作者:  Zhang, CC;  Yang, ZH;  Li, XJ;  Zhao, LS;  Guo, WJ;  Deng, W;  Wang, Q;  Hu, X;  Li, M;  Sham, PC;  Xiao, X;  Li, T
Adobe PDF(13189Kb)  |  收藏  |  浏览/下载：1649/0  |  提交时间：2024/08/19
INSIDER: Interpretable sparse matrix decomposition for RNA expression data analysis 期刊论文
PLOS GENETICS, 2024, 卷号: 20, 期号: 3
作者:  Zhao, K;  Huang, S;  Lin, CC;  Sham, PC;  So, HC;  Lin, ZX
Adobe PDF(2103Kb)  |  收藏  |  浏览/下载：1093/0  |  提交时间：2024/08/19
Estimation of causal effects of genes on complex traits using a Bayesian-network-based framework applied to GWAS data 期刊论文
NAT MACH INTELL, 2024, 卷号: 6, 期号: 10
作者:  Yin, LY;  Feng, YN;  Shi, YJ;  Lau, A;  Qiu, JH;  Sham, PC;  So, HC
Adobe PDF(2960Kb)  |  收藏  |  浏览/下载：14/0  |  提交时间：2025/04/21
Long-term metabolic side effects of second-generation antipsychotics in Chinese patients with schizophrenia: A within-subject approach with modelling of dosage effects 期刊论文
ASIAN J PSYCHIATR, 2024, 卷号: 100
作者:  Wong, KCY;  Leung, PBM;  Lee, BKW;  Sham, PC;  Lui, SSY;  So, HC
Adobe PDF(1318Kb)  |  收藏  |  浏览/下载：6/0  |  提交时间：2025/04/21
The genetic basis of onset age in schizophrenia: evidence and models 期刊论文
FRONTIERS IN GENETICS, 2023, 卷号: 14
作者:  Zhan, N;  Sham, PC;  So, HC;  Lui, SSY
Adobe PDF(758Kb)  |  收藏  |  浏览/下载：16/0  |  提交时间：2024/06/21
Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction 期刊论文
MOLECULAR PSYCHIATRY, 2022, 卷号: 27, 期号: 1, 页码: 113-126
作者:  Guan, FL;  Ni, T;  Zhu, WL;  Williams, LK;  Cui, LB;  Li, M;  Tubbs, J;  Sham, PC;  Gui, HS
Adobe PDF(1112Kb)  |  收藏  |  浏览/下载：1285/0  |  提交时间：2023/04/18
Improving polygenic risk prediction from summary statistics by an empirical Bayes approach 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: X, 页码: e41262
作者:  So HC*;  Sham PC;  hcso@cuhk.edu.hk
Adobe PDF(851Kb)  |  收藏  |  浏览/下载：1520/0  |  提交时间：2017/02/08
Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry 期刊论文
Nature Neuroscience, 2017, 卷号: **, 期号: **, 页码: published online
作者:  So HC*;  Chau CKL;  Yim SHY;  Sham PC;  Chiu WT;  Ho KS;  Lo CP;  hcso@cuhk.edu.hk
Adobe PDF(363Kb)  |  收藏  |  浏览/下载：1482/0  |  提交时间：2017/08/17
Psychiatric genetics in China: achievements and challenges 期刊论文
MOLECULAR PSYCHIATRY, 2016, 卷号: 21, 期号: 1, 页码: 4-9
作者:  Liu C*;  Saffen D;  Yao YG;  Kuo PH;  Chen C;  An Y;  Dai J;  Yue W;  Schulze TG;  Li MX;  Xue H;  Su B;  Chen L;  Shi Y;  Qiao M;  Liu T;  Xia K;  Sham PC;  Burmeister M;  liucsxx@gmail.com
Adobe PDF(250Kb)  |  收藏  |  浏览/下载：796/4  |  提交时间：2015/11/06