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Anti-angiogenesis effect of trichosanthin and the underlying mechanism 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 卷号: 430, 期号: 2, 页码: 735-740
作者:  He DX;  Jin J;  Zheng YT;  Bruce IC;  Tam S*;  Ma X*;  MTAM@cuhk.edu.hk;  maxin@jiangnan.edu.cn
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Tumor Angiogenesis  Trichosanthin  Vascular Endothelial Growth Factor  Extracellular Signal-regulated Kinases  
The anti-herpetic activity of trichosanthin via the nuclear factor-kappa B and p53 pathways 期刊论文
LIFE SCIENCES, 2012, 卷号: 90, 期号: 17-18, 页码: 673-681
作者:  He DX;  Zheng YT;  Tam SC*;  MTAM@cuhk.edu.hk
Adobe PDF(1345Kb)  |  收藏  |  浏览/下载:140/3  |  提交时间:2012/09/13
Human Herpes Simplex Virus Type 1  Nuclear Factor-kappa b  P53  Trichosanthin  
Conversion of trichosanthin-induced CD95 (Fas) type I into type II apoptotic signaling during Herpes simplex virus infection 期刊论文
MOLECULAR IMMUNOLOGY, 2011, 卷号: 48, 期号: 15-16, 页码: 2000-2008
作者:  He DX;  Yau KH;  He XH;  Shi HJ;  Zheng YT;  Tam SC*;  MTAM@cuhk.edu.hk
Adobe PDF(1790Kb)  |  收藏  |  浏览/下载:1608/3  |  提交时间:2011/10/21
Cd95 (Fas) Apoptotic Signaling  Type I/ii Apoptotic Pathway  Trichosanthin  Herpes Simplex Virus Type 1  
Trichosanthin suppresses the elevation of p38 MAPK, and Bcl-2 induced by HSV-1 infection in Vero cells 期刊论文
LIFE SCIENCES, 2006, 卷号: 79, 期号: 13, 页码: 1287-1292
作者:  Huang H;  Chan H;  Wang YY;  Ouyang DY;  Zheng YT;  Tam SC*;  mtam@cuhk.edu.hk
Adobe PDF(260Kb)  |  收藏  |  浏览/下载:90/2  |  提交时间:2010/08/24
Trichosanthin  Hsv-1  Mapk  Bcl-2  Antiviral Activity  
An inhibitor of c-Jun N-terminal kinases (CEP-11004) counteracts the anti-HIV-1 action of trichosanthin 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 卷号: 339, 期号: 1, 页码: 25-29
作者:  Ouyang DY;  Chan H;  Wang YY;  Huang H;  Tam SC*;  Zheng YT*;  zhengyt@mail.kiz.ac.cn
Adobe PDF(132Kb)  |  收藏  |  浏览/下载:105/3  |  提交时间:2010/08/24
Trichosanthin  Ribosome Inactivating Proteins  Hiv  C-jun N-terminal Kinases  Mapk  Anti-hiv Activity  Cep-11004  
Enhanced apoptotic action of trichosanthin in HIV-1 infected cells 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 卷号: 331, 期号: 4, 页码: 1075-1080
作者:  Wang YY;  Ouyang DY;  Huang H;  Chan H;  Tam SC;  Zheng YT*;  zhengyt@mail.kiz.ac.cn
Adobe PDF(492Kb)  |  收藏  |  浏览/下载:93/3  |  提交时间:2010/08/24
Trichosanthin  Hiv-1  Apoptosis  Infected Cells  Anti-hiv Activity  
Site-directed PEGylation of trichosanthin retained its anti-HIV activity with reduced potency in vitro 期刊论文
Biochemical and Biophysical Research Communications, 2004, 卷号: 317, 期号: 4, 页码: 965-971
作者:  Wang JH;  Tam SC;  Zheng YT*;  Huang H;  Ouyang DY;  Wang YY;  zhengyt@mail.kiz.ac.cn
Adobe PDF(271Kb)  |  收藏  |  浏览/下载:75/2  |  提交时间:2016/04/06
Ribosome Inactivating Protein  Trichosanthin  Hiv-1  Polyethylene Glycol  Antiviral Activity  
Independency of anti-HIV-1 activity from ribosome-inactivating activity of trichosanthin 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 卷号: 302, 期号: 1, 页码: 89-94
作者:  Wang JH;  Nie HL;  Huang H;  Tam SC;  Zheng YT*;  zhengyt@mail.kiz.ac.cn
Adobe PDF(150Kb)  |  收藏  |  浏览/下载:55/2  |  提交时间:2016/04/08
Trichosanthin  Ribosome Inactivating Protein  Human Immunodeficiency Virus Type 1  Antiviral Protein  
Relationship between trichosanthin cytotoxicity and its intracellular concentration 期刊论文
TOXICOLOGY, 2002, 卷号: 177, 期号: 2-3, 页码: 245-251
作者:  Chan WL;  Zheng YT;  Huang H;  Tam SC*;  mtam@cuhk.edu.hk
Adobe PDF(161Kb)  |  收藏  |  浏览/下载:72/3  |  提交时间:2010/08/24
Ldl Receptor-related Protein/alpha(2)-macroglobulin Receptor  Ribosome-inactivating Protein  Trichosanthin  Endocytosis  Cytotoxicity  
Anti-HIV-1 property of trichosanthin correlates with its ribosome inactivating activity 期刊论文
FEBS LETTERS, 2002, 卷号: 531, 期号: 2, 页码: 295-298
作者:  Wang JH;  Nie HL;  Tam SC;  Huang H;  Zheng YT*;  zhengyt@mail.kiz.ac.cn
Adobe PDF(149Kb)  |  收藏  |  浏览/下载:55/2  |  提交时间:2016/04/08
Trichosanthin  Ribosome Inactivating Protein  Human Immunodeficiency Virus Type 1  Antiviral Activity